Study On Quality Control And Production And Storage Technology Of Sanqi Powder In Different Parts Of Sanqi

Panax notoginseng(Burk.)F.H.Chen(Araliaceae,known as Sanqi in Chinese),is one of the best-known traditional Chinese Medicine(TCM),which powder has been used by Chongfu and external application.According to the different parts,they can divide into 3 parts which are root,rootlet and rhizome.As one of the precious Chinese herbal medicines,which shows a significant effect and expensive price,it is difficult to distinguish the medicinal sites of Sanqi powder from the market and the quality is difficult to control.The contents of R1,Rg1 and Rb1,which are the main active components of Sanqi,are different in different medicinal sites,which have a significant impact on the quality of Chinese medicinal materials.Therefore,it is important to provide foundation for its quality control in identification.The materials were divided into root,rootlet and rhizome,and crushed by "Chinese Pharmacopoeia" in corresponding Sanqi powder.Through microscopy,colorimetry,physicochemical,content determination,determination of heavy metals,and determination of polysaccharides,Sanqi powder of different medicinal sites was investigated to distinguish the quality of the three powders.In addition,this study conducted a comprehensive investigation of the content of R1,Rg1,Rb1 and ash,leachate,made by the same batch of raw materials from different batches of the raw materials,so as to optimize the production process.Finally,Sanqi powder was stored in paper bags as well as plastic bags,and the temperature was monitored in real time.The monthly change of microorganisms was monitored.The results are as follows:1.Identification of Sanqi powder in different parts:different specifications of Sanqi medicinal materials can be distinguished by appearance identification;the starch,resin tracts and catheters were distinguished by microscopy in root,rootlet and rhizome;but,according to this experimental method,calcium oxalate clusters,fibers,and fiber bundles were not detected in the root,and all of them were contained in the rhizome.The calcium oxalate clusters contained in the rootlet did not detect fibers and fiber bundles;after being identified by colorimetric analysis and analyzed by SPSS,the samples from different plants and parts of Sanqi powder can be observed in the cluster analysis chart.The samples are clearly divided into three groups,of which the root and the rhizome are highly recognizable;the color clustering of different parts of the same plant is also divided into three branches.The identification rule is not significant,and three different specifications are clustered into different groups.Therefore,different medicinal parts of the same plant have color differences and can be identified in the color check.2.Quality inspection of Sanqi powder in different parts:in total ash test,the roots are all qualified,one batch of rootlets is unqualified,and four batches of rhizomes are unqualified;acid insoluble ash tests are all qualified;The content determination of the three active ingredients R1,Rg1 and Rb1 showed that the rhizome>root>rootlet>hair root;The results of heavy metals show that the average content of heavy metals from Sanqi powder is from high to low in order of Cu,As,Pb,Cd,Hg,5.3731、0.9328、0.0239、0.0218、0.0073 mg/kg;The average total amount of heavy metals in different parts of Sanqi powder is rhizome>rootlet>hair root>root;The order of polysaccharide content is root>rootlet>hair root>rhizome.Thus,the raw material of Sanqi powder should preferably be based on the roots of different specifications of Sanqi.3.Production process optimization of Sanqi powder:The three different technologies used for the production of Sanqi powder are most suitable for the selection of process 3 from the aspects of ash content,leachables content,and uniformity of content determination.4.Changes of microorganisms during storage of Sanqi powder:Observe the aerobic,mold and yeast,Salmonella and bile salt resistance of gram-negative bacteria from 0 to 5 months at room temperature(0 to 30℃).Results Salmonella was not detected.The bile salt resistance of gram-negative bacteria were in compliance with the regulations and there was no change.Only aerobic bacteria and molds and yeasts were changed.Therefore plastic bag packaging was better than paper bag packaging.In summary,the application of microscopic identification and color recognition methods can be a good distinction to the rhizome,to provide reference for the raw material identification of Sanqi powder.The quality inspection results of Sanqi powder in different parts showed that although the content of effective ingredients in the rhizome was the highest,the rhizome,rootlet,and fluff roots that were not medicinal specifications were not suitable as the raw material of Sanqi powder from ash,heavy metals,and polysaccharides.It should be noted in practical work.