A Retrospective Study Of 61 Cases Of Granulomatous Lobular Mastitis

Background:The exact etiology and pathogenesis of granulomatous lobular mastitis are still unclear.Due to the lack of understanding of this disease,its standardized treatment plan has not been agreed.Comprehensive information on current treatment options,clinical cure rates,recurrence rates,etc.Surgical treatment can be used as the preferred treatment for this disease.Chinese and Western medicine treatment is helpful to improve the cure rate,shorten the treatment time,and reduce the recurrence,but has not reached a consensus.Objective:In this study,patients with granulomatous lobular mastitis were the subjects of the study.By reviewing clinical data,the characteristics and clinical manifestations of the disease were studied,and the best clinical treatment options for each stage were summarized.Methods:To collect granulomatous lobular mastitis cases from September 2015 to November 2017 in the Breast Department of Dongzhimen Hospital,collect and sort out the original case information,including general data,clinical conditions,and treatment status,and perform statistical analysis on the data.Results:(1)A total of 61 cases of granulomatous lobular mastitis were included in the study.All patients were female.The age of onset was 25 to 48 years old,and the average age of onset was 34.274±4.663 years old,and multiple incidences of 31-35 years old(39.34%).The incidence rate was 34.5 years postpartum(34.43%).(2)In this study,21 cases(34.43%)of nipple depression,9 cases(14.75%)of nipple discharge,9 cases(14.75%)of history of mammary gland trauma,23 cases of breast cancer history(37.70%);had oral contraceptives in 8 cases(13.11%);had taken mental drugs in 2 cases(3.28%),history of drug allergy in 8 cases(9.84%).(3)Only 3 cases(4.92%)of double breast disease occurred in 61 patients;most of them were breast tumors as the first symptom.According to the clinical stage in our hospital,17 cases(27.87%)were tumor stage and 27 cases(44.26%)were abscess stage.17 cases(27.87%)were in the sinus stage,and a few had systemic symptoms.(4)The general information of the three treatment groups,including age,course of disease,size of the tumor,etc.,were not significantly different(P>0.05)and comparable.After treatment,there was no significant difference in treatment time between the two groups(P>0.05).There was a significant difference in recurrence rate and breast shape satisfaction(P<0.05).The recurrence rate and breast shape satisfaction were higher in the TCM external teatment group.In the surgical treatment group.There were significant differences in the treatment time,recurrence rate,and breast shape satisfaction between the two groups(P<0.05).The duration of treatment in the TCM external treatment group was shorter than that of the TCM external treatment+surgery treatment group.The breast shape satisfaction was higher than that of the traditional Chinese medicine.Treatment + surgery group,but the recurrence rate is higher.There were no significant differences in treatment time,recurrence rate,and subjective breast shape satisfaction between the two groups in the sinus tract(P>0.05).However,in the Harris score,the sinus stage staging of surgical breasts was better,and the difference was statistically significant(P<0.05).Conclusions:(1)The disease occurs in middle-aged women in middle-aged and middle-aged,and the incidence rate is high in post-natal 3-5 years;(2)Onset factors:Close relationship with nipple depression,nipple discharge,trauma,milk deposition,taking birth control pills;(3)Clinical manifestations:more than one side of the disease,with breast tumor as the first symptom,more common in patients with abscess,a few with fever,nodular erythema and other systemic symptoms;(4)Treatment plan:The tumor stage and abscess stage adopt internal and external treatment of traditional Chinese medicine combined with breast shape is better,but the recurrence rate is higher;each stage of surgery does not relapse,the shape of breast lesions is small,and the combination of Chinese and Western medicines to control inflammation,to be treated After the scope is reduced,the lesion tissue is completely removed.