ObjectiveAccording to the method of Cochrane,comprehensive retrieve relevant database for the randomized control clinical trials and quasi-randomized control clinical tri als of Tuina therapy infantile anorexia.To extarct the imformation from literatures. And then to clear the clinical effect and security of Tuina in the treatment of infa ntile anorexia by the system assessment and Meta analysis.MethodsWe search the literatures from China National Knowledgeln frastructure(CNK I),WeiPu(VIP) Datebase, WanFang(WF) Datebase,China Biology Medicine disc(CB M),PubMed,Cochrane Library,Ovid Medline,EMbase,EBM.We retrieve datebase from the day that datebase was builded to 2016.1.31.Literature screening was performe d by 2 reviewers according to the standard of include and exclude.And then extar ct relevant information from the literature eventually included.The RevMan 5.3 wa s used for meta analysis. The total effective rate,recovery rate and the improveme nt of appetite were evaluted.The GradeProfiler 3.6 software was adoped for eviden ce grading.ResultsTwenty-five trials contain 1954 participants were included,1011 in experiment al group and 943 in control group.Their age range from 6 months to 13 years ol d.The course of disease between 10 days and 8 years.Effect rate:Tuina vs Zinc supplementation (RR=1.32,95%CI[1.19,1.48]).Tuina v s Chinese patent medicine (RR=1.18,95%CI[1.13,1.23]).Tuina vs xinzhi huoxiang z hengqi powder (RR=0.97,95%CI[0.89,1.05]).Recovery rate:Tuina vs Zinc supplemen tation (RR=2.26,95%CI[1.48,3.45]).Tuina vs Chinese patent medicine (RR=1.50,95% CI[1.19.1.90]).Tuina vs xinzhi huoxiang zhengqi powder (RR=1.20.95%CI[0.56.2.5 6]).Accomplished the analysis of effect rate and recovery rate about four research es.The improvement of appetite about eight researches and untoward effect of thre e researches were accomplished also. Cone I us i onsCompared with Zinc supplementation group.Tuina has better effective rate.The evidence quality is moderate.So we think the result is stable.Tuina has better effe ctive rate also.but the level of evidence is low.the result should be treated carefullTuina has better effect in improving effective rate and recovery rate than Chi nese patent medicine.The quality of evidence is "low" or "very low".These conclusi ons turned out to be unstable.Compared with xinzhi huoxiang zhengqi powder group.Tuina has no advant age in improving effective rate and recovery rate.With the evidence quality very 1 ow.it should be treated cautiously.There was no report of untoward effect in the three researches.lnfantile tuina maybe is security.but given the small sample size.it should be treated carefully. |