Non-invasive Evaluation Of Cardiovascular Autonomic Function In Elderly Patients With Diabetes Mellitus Complicated With Hypertension

Objective To investigate the noninvasive evaluation index combination of changes of autonomic cardiovascular function in old patients with hypertension and type 2 diabetes mellitus.Methods 27 old patients with single T2 DM, 27 old patients with single EH and 30 old patients with T2DM+EH were involved in the annlyses of HRV,HRT,Lorenz plot’s role and BPV.Results(1)HRV parameters: T2DM+EH group compared with T2 DM group, there were ststistical significance in SDNN(P<0.05)and p NN50(P<0.01); Compared with EH group,there were significant differences in all parameters(P<0.01) except r MSSD(P<0.05). T2 DM group compared with EH group, it was TRI(P<0.05).(2)HRT parsmeters: T2DM+EH compared with T2 DM, TS had ststistical significance(P<0.05); Compared with EH, both had ststistical significance(P<0.05); T2 DM compared with EH, it was TS( P<0.05).(3) Lorenz plot’s role area: There were no significant differences between the three groups.(4)BPV parameters: T2DM+EH compared with T2 DM, there were ststistical significance in n SSD(P<0.01)and 24 h SSD(P<0.05); Systolic blood pressure dicline rate(P<0.01) and diastolic blood pressure dicline rate(P<0.05)both had ststistical significance. Compared with EH group, n SSD and 24 h SSD both had ststistical significance(P<0.05).T2 DM compared with EH, both had significant differences(P<0.01).Conclusion Several noninvasive diagnostic technique can more comprehensively and quantificationally reflect the abnormal state of autonomic nervous function in old patients with hypertension and type 2 diabetes mellitus. The best combination among these was HRV+BPV index( prticularly SDNN、p NN50 、TRI of HRV、SSD and Systolic blood pressure dicline rate of BPV). we recommended for physicians in the selection.