Analysis Of Risk Factors Of Urinary Sepsis In PCNL Surgery

Objective: Percutaneous nephrolithotomy(PCNL)is now widely used clinically,especially for the treatment of large,complex stones obvious advantages.Urinary sepsis is one of the complications after percutaneous nephrolithotomy,fully understand the percutaneous nephrolithotomy,postoperative occurrence of urinary sepsis risk factors for the prevention and treatment of the disease has important clinical significance.Methods: The medical records of 1538 patients with percutaneous nephrolithotomy in the affiliated hospital of zunyi medical college From January 2010 to January 2017 were collected for retrospective analysis.Among them,149 patients had sepsis during and after operation.Univariate analysis comparing patients’ age,gender,urine routine(leukocyte),urine culture,stone size,stone shape,stone composition,operation time,size of puncture channel with intraoperative and postoperative correlation of sepsis(х2 test,P <0.05).The statistically significant variables in the univariate analysis were analyzed using a multivariate Logisticregression analysis to analyze the risk factors for urinary sepsis with intraoperative and postoperative correlation of sepsis.Results:In univariate statistical analysis,significant associations was observed between gender,urine routine(leukocyte),urine culture,puncture channel size,stone size,stone shape,operation time,puncture channel size with intraoperative and postoperative correlation of sepsis(P <0.05).There was no correlation between age,stone composition with intraoperative and postoperative correlation of sepsis(P> 0.05).In multivariate Logisticregression analysis showed that female,operation time(≥30min),stone size(≥3cm),staghorn or cast stones,urine routine(≥ leucocyte 100/ul),microchannel,positive urine culture were identified as risk factors for intraoperative and postoperative PCNL urosepsis.Conclusion:Female,operation time(≥30min),stone size(≥ 3cm),staghorn or cast stones,urine routine(≥ leucocyte 100/ul),microchannel,positive urine culture were identified as risk factors for intraoperative and postoperative PCNL urosepsis.