Effect Of The Modification Of Qili San On Treatment Of Hidden Blood Loss And Coagulation Function After Intertrochanteric Femoral Fractures In Elderly Patients With PFNA

Object:To explore the effect of the Modification of Qili San on treatment of hidden blood loss and coagulation function after Intertrochanteric Femoral Fractures in elderly patients with PFNA,and to open up a new way of traditional Chinese medicine treatment.Method:Thirty patients who met the inclusion criteria were randomly divided into two groups:treatment group(n = 15)and control group(n = 15).All patients met the inclusion criteria from February 2017 to February 2018.After PFNA internal fixation,the treatment group was treated with the Modification of Qili San combined with enoxaparin sodium on the basis of routine treatment,while the control group was only treated with enoxaparin sodium,and the bleeding and coagulation function indexes were observed in both groups.The changes of hemoglobin,HCT,fibrinogen,D-Dimer(D-Dimer)and DVT were compared between the two groups before and after treatment.The data were analyzed by SPSS22.0 software.The changes of above indexes and the difference of curative effect between the two groups were compared before and after treatment.Resuit:Comprehensive data comparison:there was no significant difference in age,sex composition,weight,height,number of blood transfusion,dominant blood loss and transfusion volume between the two groups(P>0.05).There was significant difference in recessive blood loss between the two groups(P<0.05).Comparison of Hb and HCT between the two groups before and after operation.1.The levels of Hb and HCT in the two groups were significantly lower than those before and after operation on the 1st and 14th day after operation(P<0.05),which indicated that there was recessive blood loss in both groups after operation.2.There was no significant difference in the level of HB and HCT between the two groups on the 1st and 7th day after operation(P>0.05),which indicated that the effect of the Modification of Qili San on the treatment of IFF by PFNA on the 1st day after operation was not obvious in the treatment of recessive blood loss.3.There was a significant difference between the two groups on the 14th day after operation(P<0.05),which indicated that the hidden blood loss was improved in both groups on the 14th day after operation.Comparison of FIB and D-Dimer before and after surgery in the two groups,1 There were significant differences in the levels of FIB and D-Dimer before and after operation between the two groups(P<0.05),the results showed that the blood was close to the peak of hypercoagulability on the first day after operation,in the both groups.2.In the two groups,the levels of FIB and D-Dimer were lower on the 14th day after than on the 7th day after operation.The difference was statistically significant(P<0.05),indicating that the blood hypercoagulability of both groups improved on the 14th day after operation.3.There was no significant difference in FIB and D-Dimer levels between the two groups on the 1st and 7th day after operation(P>0.05).which indicated that the effect of Qili San on the coagulation function of PFNA in the treatment of IFF was not obvious.4.0n the 14th day after operation,the levels of FIB and D-Dimer in the treatment group were lower than those in the control group(P<0.05),which indicated that the Modification of Qili San could effectively reduce the blood hypercoagulability after the operation of IFF.In addition,there was no DVT formation in the two groups after operation.Conclusion:The Modification of Qili San can effectively improve the hidden blood loss and blood hypercoagulability after IFF in elderly patients with PFNA.