Objective Investigation for carotid artery stenosis in patients with high risk of cerebrovascular diseases,and further analysis of the relationship between carotid artery stenosis and cerebral vascular risk factors,which contribute to the early diagnosis of carotid atherosclerotic stenosis and early prevention of stroke.Methods A total of 1461 cases of individuals at risk for cerebrovascular diseases admitted to Fujian Medical University Union Hospital from January 2013 to December2015,were divided into carotid artery stenosis group and control group according to the carotid artery color Doppler ultrasound and / or CTA examination,then analyze the relationship between carotid artery stenosis and risk factors.All data were analyzed by SPSS 19 statistical software package.Results1.476 cases were divided into carotid artery stenosis group,including 155 cases were divided into moderate or severe stenosis group,985 cases were control group.Among the carotid artery stenosis group,artery occlusion in 38 cases(2.6%),severe carotid artery stenosis in 43 cases(2.9%),moderate carotid stenosis in 74 cases(5.1%),mild carotid stenosis in 321 cases(22.0%).2.Hypertension,hyperlipidemia,diabetes were the most common vascular risk factors,followed by smoking history,atrial fibrillation / valvular heart disease,and coronary heart disease.Drinking history,family history of stroke and peripheral arterial disease were less common risk factors.The risk factors of carotid artery stenosis have synergistic effect.With the increase of risk factors,the risk of carotid artery stenosis increased.The risk of carotid artery stenosis increased to 1.36 times in individuals with3 risk factors(?2=7.575,P<0.05),the risk of carotid artery stenosis increased to 1.42 times in individuals with more than 3 risk factors(?2=7.827,P<0.05).3.In carotid artery stenosis group,the proportion of male,hypertension,history ofsmoking and alcohol drinking was significantly higher than those in the control group(P< 0.05);and the stenosis of atrial fibrillation / valvular heart disease was lower than that of the control group(P < 0.05).Multivariate logistic regression analysis revealed that men,hypertension,drinking history were independent risk factors for carotid stenosis.4.In moderate or severe stenosis group,the proportion of male,hypertension,smoking and drinking history were significantly higher than those in the control group(P < 0.05).Logistic regression analysis showed that male,hypertension were independent risk factors for moderate or severe carotid stenosis,and hypertension is the primary risk factor(hypertension: OR=1.970,95%CI[1.262~3.074],P=0.003).5.A total of 559 cases of high-risk individuals had more than 3 cardiovascular risk factors with nonspecific cerebral ischemia symptoms.Among them,carotid artery occlusion in 11 cases(2%),23 cases of severe carotid artery stenosis(4.1%),29 cases of moderate carotid artery stenosis(5.2%),146 cases of mild carotid artery stenosis(26.1%).The proportion of individuals with history of smoking and alcohol consumption in moderate or severe carotid stenosis group was significantly higher than that in normal individuals(respectively 58.7% VS 43.4% and 28.6% VS 16.9%,P<0.05).Conclusion1.The study of carotid artery investigation aimed at people aged 40-79 years old with nonspecific cerebral ischemia symptoms and more than one risk factor.Among them,moderate or severe carotid stenosis prevalence rate was 10.6%.In the high-risk individuals with more than 3 cardiovascular risk factors,the prevalence of moderate or severe carotid artery stenosis was 11.3%.The risk factors have a synergistic effect on the occurrence of carotid stenosis.With the increase of risk factors,the risk of carotid artery stenosis increased.2.Although studies have shown that common people do not need to screen for carotid artery stenosis with the carotid artery color Doppler.However,individuals with atypical symptoms,especially individuals with one of male,hypertension,drinking history and smoking history,should pay attention to improve the awareness of earlyscreening and primary prevention of stroke. |