A Clinical Study Of MOCA Scale Analysis Between Asymptomatic Carotid Stenosis Associated And Mild Cognitive Dysfunction

Objective:Early asymptomatic carotid stenosis and cognitive impairment of MOCA score correlation and neuropsychological characteristics.Methods:According to standard into and out from the hospital neurology clinic, hospital, and physical examination center selected asymptomatic carotid stenosis cases of91cases of patients with carotid artery doppler ultrasound examination,according to the degree of carotid stenosis patients divided into stenosis group43cases,(stenosis rate of50%or higher) and control group48cases (stenosis rate<50%), case selection and grouping of homogeneity of the above risk factors as much as possible.Uses the Montreal cognitive assessment scale for patients with cognitive assessment (MOCA), the degree of carotid stenosis and cognitive function of index correlation analysis,to observe the relationship between the degree of carotid stenosis and cognitive dysfunction and carotid stenosis patients exist neuropsychological characteristics of cognitive impairment.Uses SPSS17.0software for statistical analysis, measurement data with x±s according to the comparison between the two independent sample mean using t test, variance when not together with approximate t test; Count data to constitute relative abundance ratio (%), according to use chi-square test; Multiple factors analysis using Logistic regression.Pearson correlation analysis were carried out to study the relationship between the carotid stenosis and cognitive function. With P<0.05for the difference was statistically significant.Result:(1) the asymptomatic carotid artery stenosis degree and MOCA scores, single factor correlation analysis results show that R=0.81, P<0.05, with statistical significance, namely the asymptomatic carotid stenosis degree negative correlation with MOCA score, which was asymptomatic carotid stenosis and cognitive dysfunction.(2) the MOCA scores in patients with stenosis group, alternate connection test, copy the cube, clocks, delayed recall test scores are lower than the control group, with significant difference between groups (P<0.05), and naming, attention, sentence repetition, abstract, language fluency, directional forces, there was no statistically significant difference between groups (P>0.05).Conclusions:(1) the asymptomatic carotid artery stenosis were risk factors of mild cognitive dysfunction, and can be used as predictors of early cognitive dysfunction, and early intervention of asymptomatic carotid stenosis can bring benefit to patients.(2) the asymptomatic carotid artery stenosis in patients with mild cognitive impairment, main show is executive function (alternate connection test), depending on the spatial structure features copied cubes,(clock) and delayed recall function is significantly impaired (delayed recall), named force, attention, language ability (sentence repetition, language fluency, abstract, directional forces, there was no significant difference between groups (P>0.05).(3) the MOCA scale can be used for asymptomatic carotid stenosis caused mild cognitive dysfunction screening.