Treatment Of Perimenopausal Syndrome Curative Effect Of Tonifying Spleen And Stomach Decoction To Purge Yin Sheng Yang

Objective:Based on the observation of clinical therapeutic effects of Bupiwei Shengyang Sanhuo Decoction on perimenopausal syndrome,this paper discuss the characteristic and outline of the treatment of this syndrome using Spleen and Stomach with the aim of providing the supportive information for the clinical treatment of perimenopausal syndrome by means of the jianpi yiqi method.Method:About 120 cases of perimenopausal syndrome in the traditional Chinese medicine apartment of Jincheng Coal Industry Group during the period of March 1,2015-July 30,2015 was randomly divided into traditional Chinese medicine group(60 patients)and western medicine group(60 patients).The traditional Chinese medicine group was treated with Bupiwei Shengyang Sanhuo Decoction as the main treatment and the other one with HRT as a treatment.The content of blood follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)were measured in these two groups before treatment and after six-month treatment,and then adopted the modified Kupperman index to evaluate the treatment situation of these two methods for perimenopausal syndrome between before treatment and after treatment.In this study,the SPSS software was used for data-processing and test of significance was conducted using student’s test(t-test).Results:The results showed that the difference in the contents of blood follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)hormone in patients between these two groups before treatment were non-significant at the confidence level of a=0.01.Similarly,after six-month treatment,the difference in the contents of the above indicator in patients between these two groups was non-significant.However,for the patients in each group,the difference in the contents of the above indicator in patients between before treatment and after six-month treatment was significant,this showing that these two method having curative effect.According to modified Kupperman method,total effective rate for Chinese medicine group was 90% and for western medicine group was 72%.In aspect of safety,no special occurred discomfort occurred for two group patients and there was no obvious histological abnormality in the blood routine,routine urine,feces routine,electrocardiogram(ECG),liver function,renal function.Conclusion:For perimenopausal syndrome patients,tonifying spleen and stomach yin and purging fire sun Tang can significantly lessen some symptoms,have higher cure rate after the specified course and improve neuropsychiatric symptoms better than the western medicine group.It not only can increase serum E2 level and decrease blood levels of FSH,LH,but also can regulate the immune function of the organism without the adverse reaction.In this study,the modified Kupperman score method was adopted to evaluate the treatment situation of two groups of patients with perimenopausal syndrome before treatment and after six-month treatment and objectively indicated the efficacy of the method,and discussed the mechanism of this method.And this study would provide useful reference for traditional Chinese medicine in the treatment of perimenopausal syndrome patients.