Effects Of Trimetazidine Hydrochloride On Patients With Coronary Heart Disease And Erectile Dysfunction

Objectives: Coronary heart disease with erectile dysfunction in the application of coronary heart disease secondary prevention of coronary heart disease at the same time combined with trimetazidine hydrochloride on its erectile function,analysis of trimetazidine hydrochloride to improve coronary heart disease with erectile dysfunction in patients with Sexual.Methods:1 Select from January 2016 to September 2016 in our hospital Cardiology successfully underwent coronary angiography,coronary CTA and myocardial perfusion scan definite diagnosis of coronary heart disease and erectile dysfunction in men combined 60 patients.All patients before treatment,ask the relevant medical history,physical examination,blood routine examination,ECG and echocardiography and other tests.In this study,two groups of comparative study design randomly selected patients were divided into two groups: one for the application of trimetazidine hydrochloride group,the other group did not use the song hydrochloride trimetazidine group.Two other factors the same(definite diagnosis of coronary heart disease in patients with erectile dysfunction merger,before the patient is not applied too trimetazidine hydrochloride and sildenafil and other drug treatment and secondary prevention of coronary heart disease are applied conventional drug treatment),a single Blindness,Erectile Function International Questionnaire-5(IIEF-5)IIEF scores were assessed for both groups of patients to evaluate erectile function.A total of three times the data acquisition,that enrolled patients with a first assessment of erectile function at admission,the second assessment 1month after the 3rd assessment three months later,the patients were asked notinterrupted medication.2 Using SPSS21.0 statistical software for statistical analysis,measurement data using mean ± standard deviation(?x ± s)that the analysis method using repeated measures analysis of variance and t-test design;Count data using several frequency representation,analysis using chi-square test;Level data and non-normal distribution of measurement data using rank sum test analysis,Fisher’s exact test.P <0.05 was considered statistically significant difference represented.Results:1 For erectile dysfunction in coronary artery disease patients there was a significant difference(P <0.05)in the application of trimetazidine hydrochloride group and not with hydrochloric acid trimetazidine group IIEF score.2 There was also a significant difference in the time of drug use in the trimetazidine group,There was a significant difference(P <0.05)between the IIEF score and the use of trimetazidine hydrochloride IIEF score after 1 month of trimetazidine hydrochloride;There was a significant difference in IIEF score between 3 months after the application of trimetazidine hydrochloride and the use of trimetazidine hydrochloride for 1 month(P <0.05).3 Unused trimetazidine hydrochloride was no significant difference(P>0.05)trimetazidine group on the time factor.Conclutions:1 The combined application of erectile dysfunction in coronary heart disease Hydrochloride Trimetazidine can improve the patient’s erectile function.2 With the continuous application of trimetazidine hydrochloride process,in the short term(time ≤3 months)can improve erectile function,the longer the application time,erectile function improved more significantly.3 Secondary prevention of coronary heart disease drug treatment forerectile dysfunction,no significant effect.