Early Rehabilitation Combined With Dl-3n-butylphthalide Injection In The Treatment Of Acute Cerebral Infraction

Objectives:Under the use of d1-3n-butylphthalide injection,to compare the efficacy of medicine treatment combined with early rehabilitation with the simply use of medicine in treatment for patients with acute cerebral infarction,to assess the motor function and ADL of patients used early rehabilitation in treatment of acute cerebral infarction in 1 week and 2 weeks,to analyze the value for the early rehabilitation.Methods:Patients with acute cerebral infarction treated with d1-3n-butyphthalide injection within 48h were random divided into rehabilitation group(n=29)and control group(n=30),the rehabilitation group’s patients were given the early rehabilitation within 3d after inpatient,from the onset of neurological treatment in hospital until the 2 weeks of treatment,assess all patients’ FMA,BI in the first selected,the 1 week and the 2 weeks of treatment,and to analyze the recovery of patients,motor function and ADL under different conditions.Results:1.At the time of enrollment,there was no significant difference in FMA motor function scores between rehabilitation group and the control group(P>0.05).The FMA motor function scores gradually increased from 25.32±5.76 to 42.63±8.009,indicated that the control group under drug treatment,patients’ motor function had been restored.The 1 week’s scores FMA motor function in the control group were significantly higher than those in the enrollment(P<0.01),so was the difference between the 2 weeks and the 1 week(P<0.05),both were statistically significant.The rehabilitation group’s FMA raised from 27.55±5.94 to 50.48±6.13.There was no significant difference in FMA motor function scores between the two groups in 1 week(P>0.05),while the differences in 2 weeks were statistically significant(P<0.05).2.There was no significant difference in BI score between the rehabilitation group and the control group(P>0.05)at the time of enrollment,on the 1 week assessment.,although the control group’s BI score gradually increased during the observation period,changed from 19.52±6.10 to 35.67±7.74,increased 16.61 scores approximately,but rehabilitation group was increased from 20.52±6.03 to 40.42±7.48,raised about 19.90 scores,the increased scores of rehabilitation group was more than the control group,the differences were statistically significant(P<0.05).Between every assessment’s BI scores in both groups had significant difference(P<0.05).Conclusions:1.Under the use of dl-3n-butylphthalide injection,compare the efficacy of medicine treatment combined with early rehabilitation with the simply use of medicine in treat of patients with acute cerebral infarction,early rehabilitation therapy can effectively restore the patients’ motor dysfunction,improve the ADL for patients with acute cerebral infarction.2.The application of dl-3n-butylphthalide injection for treatment of acute cerebral infarction patients,patients’ motor function and ADL’s improvement was most obvious in the first week.3.Patients with acute cerebral infarction in the treatment of dl-3n-butylphthalide injection and combined with early rehabilitation,the efficacy in motor function and ADL in the 1 week had no significant difference,the reason may be the use of dl-3n-butylphthalide injection’s therapeutic effect and the rehabilitation time is short.