Comparision Of Continuous Anterior Chamber Infusion And Ophthalmicviscoelastic Agent In Phacoemulsification On The Postoperative Ocular Surface

Objective : To compare the influence of continuous anterior chamber infusion and ophthalmicviscoelastic agent in phacoemulsification on the postoperative ocular surface.Methods : This was a prospective,randomized controlled trial.Sixty-eight eyes of age-related cataract undergoing phacoemulsification were included.Patients were randomly divided into Groups A and B.Cataract surgery was performed by phacoemulsification with continuous anterior chamber infusion in Group A(34 eyes),and by phacoemulsification with an ophthalmic viscoelastic agent in Group B(34 eyes).Dry eye symptoms,break-up time of tear film(BUT),cornealfluorescent staining and integral(corneal fluorescent staining,CFS),SchirmerⅠ test without anesthesia(SⅠt)were measured preoperatively and on postoperative days 1,7 and 30.Results : 1.Compared with the preoperative index of both groups,the BUT on the1 th,7th and 30 th postoperative day was significant shorter,the CFS was significant increased on postoperative day 1 and days 7,the SⅠt was significant increased on postoperatively day1 and decreased on postoperatively days 7.All of the differences mentioned above were statistically significant(P<0.05).2.There was significant difference between group A andgroup B in the change of CFS(3.47±0.71 vs.2.94±0.78,P<0.05)on postoperatively day 1.There was significant difference between group A and group B in the change of SⅠt(4.50±1.60 vs.3.65±1.18,P<0.05)on postoperatively day 1.In both group,no signification difference in the change of various observational index on postoperatively days 7 and 30.Conclusion : Continuous anterior chamber infusion during phacoemulsification could lead to the slightly injury of corneal epithelium and increase tear secretions on the early period of postoperation,while in middle-late period,it did not exacerbate the ocular surface injury.