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Revman Meta-analysis And Evaluation Of Gegen Huangqin Huanglian Decoction Treatment Of Pediatric Rotavirus Enteritis Randomized Controlled Trials

Posted on:2018-03-14Degree:MasterType:Thesis
Country:ChinaCandidate:J Y ZengFull Text:PDF
GTID:2334330515991852Subject:TCM clinical basis
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Research purposes:This paper mainly contains two major parts.Firstly,the literature review of theoretical research,modern clinical application.Secondly,the research of Evidence-based medicine and system treatment of Gegen Huangqin Huanglian Decoction.Comprehensive search,collection,reading,statistics and screening of randomized controlled trials of clinical research literature of Gegen Huangqin Huanglian Decoction.Clinical results shows that Gegen Huangqin Huanglian Decoction is mainly used to treat Pediatric Rotavirus Enteritis.Based on the results,literatures with the same research contents and objectives were classified and divided into two groups.Used Meta-analysis software provided by the Cochrane system to perform statistical and analysis for two groups of data.Finally,based on the principle of evidence-based medicine will get the best treatment program for each disease.Therefore recommended a set of treatment program for Pediatric Rotavirus Enteritis.Object of study1 Extracts from journal publications for the period 1949 March 2017,on application of Gegen Huangqin Huanglian Decoction.2 Gegen Huangqin Huanglian Decoction and Integrative Medicine treatments for Pediatric Rotavirus Enteritis on randomized controlled trials and journal literature.Research methods1 Title:Based on the principle of traditional Chinese medicine syndrome differentiation and Western medicine internal control of Pediatric Rotavirus Enteritis,and name the title as " RevMan Meta-analysis and evaluation of Gegen Huangqin Huanglian Decoction treatment of Pediatric Rotavirus Enteritis randomized controlled trials."2 Search of literatures:Set keywords as follows:Gegen Huangqin Huanglian Decoction,Gegen Qinlian Decoction,addition and subtraction of Gegen Huangqin Huanglian Decoction,compound of Gegen Huangqin Huanglian Decoction,addition and subtraction of Gegen Qinlian Decoction,compound of Gegen Qinl ian Decoction.Pediatric Rotavirus,treatment of Pediatric Rotavirus,Pediatric Rotavirus Enteritis,treatment of Pediatric Rotavirus Enteritis.3 Data processing through use of Meta-analysis software provided by the Cochrane system to analyzed statistically two groups of data.Research contentAnalysis of Gegen Huangqin Huanglian Decoction for treatment of children's Pediatric Rotavirus Enteritis by Meta-analysis Statistical Software from Cochrane System.The statistical results of two variables classification as below:1.Two variables classification:1.1 Gegen Huangqin Huanglian Decoction Vs Basic Western medicine therapy.1.2 Gegen Huangqin Huanglian Decoction + Basic Western medicine therapy Vs Basic Western medicine therapy.2.Continuous variables classification:Integrative medicine treatment<Basic Western medicine therapy to compare healing time of clinical symptoms of Pediatric Rotavirus Enteritis.2.1 Time of diarrhea SMD2.2 Time of fever SMD2.3 Time of vomiting stop SMD2.4 Dehydration correction time SMD2.5 Time of bloating stop SMD 2.6 Total treatment time SMDResearch resultMeta-analysis software provided by Cochrane system was used to analyze the therapeutic effect of Gegen Huangqin Huanglian Decoction in the treatment of Pediatric Rotavirus Enteritis.The statistical results of dichotomous and continuous data as below:1.Two variables classification:1.1 Gegen Huangqin Huanglian Decoction>Basic Western medicine therapy1.2 Gegen Huangqin Huanglian Decoction + Basic Western medicine therapy>Basic Western medicine therapy2.Continuous variables classification:2.1 Integrative medicine treatment time of diarrhea SMD<Basic Western medicine therapy time of diarrhea SMD2.2 Integrative medicine treatment time of fever SMD<Basic Western medicine therapy time of fever SMD2.3 Integrative medicine treatment time of stop vomiting SMD<Basic Western medicine therapy time of stop vomiting SMD2.4 Integrative medicine treatment time of dehydration correction SMD<Basic Western medicine therapy time of dehydration correction SMD2.5 Integrative Medicine treatment time of abdomen bloated stop SMD<Basic Western medicine therapy time of abdomen bloated stop SMD2.6 The total treatment time SMD of Integrative Medicine<The total treatment time SMD of basic Western medicineResearch results and proposed treatment for pediatric rotavirus enteritis:Based on Research results,the author and Mentor Professor Chen Ming proposed treatment for Pediatric Rotavirus Enteritis as below:1.Chinese medicine prescription:Gegen Huangqin Huanglian Decoction(Pueraria thomsonii Benth,Scutellaria baicalensis Georgi,Coptis chinensis Franch,Glycyrrhiza uralensis.)2.compatibility:2.1 Spleen Deficiency:Atractylode macrocephala Koidz.,Dioscorea opposite Thunb,Lablab purpureus.2.2 Dampness:Atractylodes Lancea,Alisma plantago-aquatica Linn,Smi lax china,Plantaginis semen.2.3 Spleen and stomach qi stagnation:Saussurea costus,Bupleurum2.4 Spleen and stomach Deficiency:Atractylodes macrocephala Koidz.,Zingiber officinale Rose.,2.5 Vomiting or greasy coating tongue:Pinellia ternata,Agastache rugosa2.6 Dysentery due to heat pathogen:Lonicera japonica Thunb charcoal3.Basic Western medicine therapy:to correct the electrolyte,balance acid-base and nutritional support.
Keywords/Search Tags:Gegen Huangqin Huanglian Decoction, Diarrhea, Recommended treatment options of Pediatric Rotavirus Enteritis, evidence-based medicine, Meta-analysis
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