Study On The Relationship Between NO6 Group And NO14V Lymph Node In Gastric Cancer

Objective:Lymphatic metastasis is the main pathway of gastric cancer.the clinicopathological factors influencing the metastasis of pylorus(6 groups)and its three subgroups of lymph nodes(6a,6i,6v)were analyzed to investigate the effect of lymph node metastasis 14 v group lymph node metastasis,as well as the 14 v group lymph node on the prognosis of the patients.Method:The clinical Pathophysiology data of 398 patients undergoing radical gastrectomy(D2 or D1 +)were retrospectively collected from January 2013 to December 2015 at xxxx University First Affiliated Hospital of Gastrointestinal Surgery.(6a,6i,6v)in the three subgroups of the pylorus(6 groups)and their three subgroups,and to explore the lymph node metastasis of group 4v in the group of lymph node metastasis.The effect of lymph node dissection on the prognosis of patients with 14 v group.Result:1.Among the 398 patients,there were 181 patients with lymph node metastasis,accounting for 45.6% of the total.There were 53 patients with lymph node metastasis.There were 19 patients with lymph node metastasis,and the metastasis rate was 35.8%(19/53).There were 15 patients with lymph node metastasis in 6i group,the metastasis rate was 26.4%(14/53),20 patients with 6v lymph node metastasis,The transfer rate was 17.0%(9/43).There were 136 lymph nodes in the 6a subgroup.The number of lymph nodes(1.86 ± 2.54)was obtained in each patient,including 23 positive lymph nodes and 16.9%(23/136)(0.50 ± 1.2)pieces,16 metastatic lymph nodes and 18.6%(16/86)of lymph node metastasis.There were 88 lymph nodes in the 6v subgroup,and the number of lymph nodes in the 6th subgroup was 1,(0.93 ± 1.07)pieces,22 metastatic lymph nodes and 25.0%(22/88)in lymph node metastasis.There was no significant difference in lymph node metastasis between the three subgroups(P = 0.342).The single factor analysis of lymph node metastasis in 6 and 6 groups showed that the lymph node metastasis and tumor size,tumor differentiation degree,N,M staging(p <0.05)3.No.6a metastasiswas correlated with No.3(P <0.001)、 No.4sb(p <0.001)、No.4d(p <0.001)、No.5(p < 0.001)、No.8a(p<0.001)、No.9(p<0.001)lymph node metastasis but without in No.14 v group(p = 0.436).No.6i metastasiswas correlated with No.4sb(P <0.001)、 No.4d(p <0.001)、No.5(p <0.001)、No.7(p < 0.001)、No.8a(p<0.001)、No.9(p<0.001)lymph node metastasis but without in No.14 v group(p = 0.597).No.6v metastasiswas correlated with No.3(P <0.001)、 No.4sb(p <0.001)、No.4d(p <0.001)、No.5(p < 0.001)、No.7(p<0.001)、No.8a(p<0.001)、No.9(p <0.001)lymph node metastasis,also in No.14 v group(P <0.001).4.Multivariate analysis showed that the 6v group lymph node metastasis is not 14 v cleaning group of patients with independent prognostic factors.Subgroup analysis showed that the 3-year survival rates were 42.9% and 57.6%(p = 0.005)in the 14 th group of patients with TNMIII,and the lymph node metastasis in the 14 v group was an independent prognostic factor for TNMIII patients(HR = 1.694,95% CI: 1.071-2.680,p = 0.024).The prognosis of lymph node metastasis in group 14 v was correlated with tumor maximal diameter,TNM staging and distant metastasis(all p <0.05).Conclusion:1.distant metastasis and lymph node metastasis of group 4a in group 4a were the independent risk factors of lymph node metastasis in group 6v.Group 6 lymph node metastasis was a reliable predictor of lymph node metastasis in group 14 v.2.I / 11 patients with 14 v group lymph node metastasis rate is low,stage IV patients with poor prognosis,14 v group lymph node dissection does not improve the survival of such patients.3.Ill stage of the lower and middle cancers,such as the discovery of 6v lymph node metastasis,14 v group lymph node metastasis rate is relatively high,preventive scan of the 14 v group lymph nodes can improve the prognosis.