| Objective:1.To summarize the characteristics of chronic gastritis(CG)in Chinese medicine by syndromes analysis.2.To observe the curative effect of Jianpi Xiaozhan on spleen deficiency syndrome,and to provide reference for clinical treatment of CG.Methods:1.To collect from October 2011-October 2016 Anhui University of Traditional Chinese Medicine First Affiliated Hospital cadres Department of spleen and stomach inpatient department were diagnosed with chronic gastritis in all patients 483 cases.The patients were collected using syndromes dialectical methods to analyze their symptoms and analysis.2.Sixty-four patients with chronic gastritis with pixu qizhi type who were hospitalized in the Department of Spleen and Stomach in Anhui Province from Decembe 2015 to December 2016 were selected.The patients were divided into two groups by random number table method.32 cases were observed in the observation group(32 cases of inflamed fever and omeprazole + omeprazole + mosapride);32 cases in the control group(omeprazole + mosapride)The The rats were sacrificed at 1 hour after the morning and evening,and the clinical symptoms score,gastroscopy,pathology,gastrin17(G-17),liver and kidney function changes.Results:1.By collecting 483 cases of patients diagnosed with CG in our department,the patients were collected and analyzed by dialectical method.Can be found in the pathogens of chronic gastritis mainly distributed in the stomach,spleen,liver,gallbladder,and the frequency of occurrence from high to low followed by stomach> spleen> liver>gallbladder;chronic gastritis disease syndromes distribution to qi stagnation,Qi deficiency,yang deficiency,wet and more common,and the frequency of occurrence followed by qi stagnation> qi deficiency> yang> wet> hot> sputum> blood stasis.2.Jianpi Xiaoban Fang in patients with chronic gastritis spleen qi stagnation of the clinical observation of the following conclusions:2.1 The clinical efficacy of treatment after treatment found that the treatment group Jianpi Xiaoban combined with mosapride and omeprazole treatment of chronic gastritis spleen qi stagnation in patients with a total effective rate was 87.5%,the control group with mosapride and omeprazole The total effective rate of patients treated with azole was 56.25%,and the difference was statistically significant by chi-square test(P <0.05).Indicating that the clinical efficacy of the treatment group was significantly better than the control group.2.2 Comparison of the total clinical symptoms of the two groups of patients,indicating that: before treatment,the two groups of patients with clinical symptoms of the total score by statistical analysis(P> 0.05)was no statistically significant,the two groups of patients with comparable.The total score of clinical symptoms before and after treatment in both groups was statistically analyzed,P <0.05,the difference was statistically significant.The scores of the two groups were compared before and after treatment,and the difference was statistically significant.The difference between the two groups was also statistically significant.Description of spleen and expansive can effectively improve the patient’s epigastric fullness,stomach pain,loose stools,mouth pale,weak lazy words,belching,loss of appetite symptoms.2.3 Comparison of the two groups of patients in the pathological results,indicating that:after treatment,the total effective rate of chronic inflammation: 93.75%,the total effective rate of glandular atrophy 60.00%,the total effective rate of intestinal 71.43%,the total effective rate of dysplasia 25.00 %,Significantly higher than the control group of chronic inflammation 62.5%,glandular atrophy 41.67%,intestinal 33.33%,dysplasia20.00%.Statistical analysis,the treatment group and the control group of chronic inflammation,atrophy,compared with the difference was statistically significant,intestinal,heterosexual hyperplasia was not statistically significant.The total effective rate of the treatment group was higher than that of the control group,which indicated that the spleen and anti-swelling side had significant effect on chronic inflammation ofgastric mucosa and had the effect of relieving gastric atrophy.2.4 The level of gastrin in the treatment group was significantly lower than that before treatment(P <0.05).The level of gastrin in the control group was significantly higher than that before treatment(P <0.05).The difference was statistically significant(P<0.05).The improvement of gastrin level in the treatment group was significantly better than that in the control group(P <0.05),the difference was statistically significant.This study shows that spleen deficiency can effectively reduce the level of gastrin,so as to protect the gastric mucosa from gastric acid,pepsinogen and other erosion,to a certain extent,ease the process of gastric cancer.Conclusion:1.From 2011 to 2016,the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine in the Department of Gastroenterology,chronic gastritis patients with spleen qi stagnation type most common.2.The clinical effect of spleen deficiency and qi stagnation in patients with chronic gastritis was significantly higher than that in the control group(P <0.05).Conclusion:The spleen deficiency and qi stagnation can improve the atrophy and intestinal mucosa of patients with chronic gastritis,At the same time can effectively reduce the level of blood gastrin 17,and before and after treatment of patients with the safety indicators were normal,indicating that spleen deficiency can be effective in the treatment of chronic gastritis spleen qi stagnation patients,is safe and reliable prescription. |
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