Clinical Value Of Combining Use Of Urine BTA Stat Test,Urine Cytology And Transabdominal Ultrasonography In Diagnosis Of Bladder Cancer

Purpose:To discuss the value of BTA,urinary system color Doppler ultrasound examination and exfoliative urinary cytology combined examination in bladder cancer diagnosis.Method:forward-looking research was conducted on 50 suspected cases of bladder cancer hospitalized in Bethune the third hospital attached to Jilin University,and the patients are all with different level of intermittent painless visible hematuresis or non-hematuresis frequent micturition,urgent urination,odynuria or other symptoms related to bladder cancer.Urinary lesion has been excluded through iconography examination with routine urine test,urinary cytology,urine BTA,abdominal color Doppler ultrasound examination,cystoscope and other relevant examinations so as to observe the sensitivity,specificity and diagnosis coincidence rate of each examination program.Finally,compare the the sensitivity change after mutual combination by means of previous combined examination.Result:the 50 suspected cases of bladder cancer were pathologically diagnosed through cystoscope as 34 bladder transitional cell carcinoma(12 low level,22 high level)and 16 cases of benign disease of urinary system(in which papillary epithelioma,BPH,glandular cystitis,cystitis granuloma can be seen).In the research,the sensitivity of color Doppler ultrasound examination is 70.58 percent,specificity 93.75 percent,one false positive case.Sensitivity of exfoliative urinary cells is 29.41 percent,specificity 93.75 percent,also one false positive case.And the patient in this case shows positive in urine BTA stat,which needs close follow-up observation.The sensitivity of BTA stat is 76.47 percent,specificity 81.25 percent.32 cases of bladder carcinoma were diagnosed through the three-combined examination with 94.12 percent of sensitivity of the combined diagnosis.When compared with each individual examination,there are statistic difference(P<0.05),which shows that after the three-combination,the sensitivity improves,thus paving way for the diagnosis of bladder cancer.The comparison between the three-combination and cystoscope shows no big difference(P>0.05),showing that the sensitivity after the three-combination is similar to that of cystoscope,so the three-combination examination is a convenient,effective,non-invasive clinic examination method.For those patients who have taboos in cystoscope or with strong resistance,the three-combination examination can be conducted to replace cystoscope tentatively,but when the result of the combination examination shows positive,cystoscope biopsy is needed to make final diagnosis.In the process,the sensitivity is 76.47 percent after the combination of traditional color Doppler ultrasound examination and urinary cytology,which shows statistic difference with the result of cystoscope(P=0.008).Later,with the help of urinary BTA can the level of cystoscope examination effect be fulfilled,which shows that BTA has practical value in clinic trial and worths publicizing.Conclusion:BTA Stat,color Doppler ultrasound examination,diagnosis of bladder cancer through urinary cytological combined examination can improve the sensitivity so as to partly replace the effect of cystoscope,and BTA has practical value in clinic trail.