The Clinical Study Of Baimai Ointment Combined With Tibetan Medicine Dipping On Patients With Limb Spasm After Stroke

ObjectiveThe study is to make clear the clinical effect of Baimai ointment with Tibetan Medicine dippng on patients with limb spasm after stroke,and whether it can improve limb motor function and the activities of daily living,and to find a new and safety method of curing the limb spasm after stroke.MethodsThis study comes from the" 12th five-year" scientific and technological support program which about the treatment of limb spasm after stroke.Patients who met the inclusion criteria were ramdonly divided into three groups by central computer:A group,B group,C group.A group 25cases,B group 29 cases,C group 23 cases.All the patients recived basic treatment and modern rehabilitat ion training.Besides,B group recived Baimai ointment with manipulation treatments and C group recived Baima i ointment、manipulation and Wuwei Ganlu Yaoyu Granules treatments.All the patients received treatments for four weeks.Before and after treatment,all the patients were evaluated from the three aspects:modified Barthel index(MBI),simplified Fugl-Meyer function assessm ent(FMA)and modified Ashworth scale(MAS),and then analysised the data by statistical software 21.0 to compare which group get the best rehabilitation.Results1.Baseline comparison:There have no difference among the three groups in the aspects of basic information(including sex、age、Course of disease、lesion characteristics)and the scores of MMSE,MAS,FMA and MBI before treatment(P>0.05).2.The comparison of scores before and after treatment in the same group:The degree of limb spasm of the three groups got relief,and the score of MAS had decreased,scores of FMA and MBI had been improved compared with that before the treatment(P<0.05).3.The comparison of the effect among the three groups after the treatment:the scores of MAS and FMA of C group changed more obviously than that scores of A group,and had statistic sence(P<0.05);the scores of MAS of C group changed more obviously than that scores of B group,and had statistic sence(P<0.05);The scores FMA of B group had been changed more obviously than that scores of A group,but has no statistic sence(P>0.05);The scores of MBI of there groups had been improved after treatment,and had little statistic sence(P>0.05).4.Stratified comparison:According to statistical results(about age and course of stroke),changes of scores of the MAS、MBI and FMA ware not related to age and course of stroke.5.One patient were weeded out of the study who was diagnosed with cancer.Conclusion1.The three methods all could relieve the limb spasm,C group was best in the three groups:The difference between A and B had no stastic sence and probably because the cases were not enough to estimate and the number of the two groups were different.2.The three methods all could improve limb motor function and the activiti es of daily living.C group was best in the three groups in the aspect of limb motor function.There were insignificant difference between A and B group in effectiveness,and the result probably because the cases were not enough to estimate and the number of the two groups were different,so did the difference in the aspect of activities of daily living among the three groups.3.Stratified comparison showed that changes in scores of the MAS、MBI and FMA were not related to age and course of stroke.The result may be negative becourse of small sample size、various aspects interact with each other and so on。4.No adverse reactions were found in this study,the method were safety.