| ObjectiveThe study aimed to evaluate the effect of five-element music therapy combined with midnight-noon ebb-flow theory on anxiety, sleep quality, daytime fatigue, quality of life, burden of caregiver and level of blood pressure and heart rate among patients with anxiety induced by chronic heart failure (CHF). It can promote the research on both time effect and standardization of five-element music therapy, provide foundation for mechanism research, furtherly promote the traditional Chinese medicine of time.MethodsThis study was a randomized controlled trail. Accroding to the inclusion criteria, From January 2015 to May 2015,78 patients from the affiliated hospital of Chengdu University of TCM were included. They were divided into experimental group (n=39) and control group (n=39) by random number table. On the regular basic treatment of CHF, we optimized the procedure of five-element music therapy before intervention, then the experimental group was performed five-element music therapy combined with midnight-noon ebb-flow theory, while the control group was performed five-element music therapy. Several scales such as the Self-rating Anxiety Scale (SAS), Pittsburgh Sleep Quality Index (PSQI) and The Flinders Fatigue Scale (FFS) were mearsured in four time points, which were pre-intervention, fourth week, eighth week and four weeks pro-intervention. Meanwhile, Quality of Life Questionnaire Minnesota in Heart Failure subjects (MLHFQ), the Dutch Objective Burden Inventory (DOBI) and level of blood pressure and heart rate were mearsured in three time points, pre-intervention, eighth week and four weeks pro-intervention.ResultsTotally,70 patients completed all data collection, each group 35, with 7 cases were excluded. In the experimental group,1 case rejected and 3 cases lossed, while in the control group,2 cases rejected and 2 cases lossed.1. Anxiety Symptom. The SAS score in control group at fourth, eighth week and four weeks pro-intervention were lower than that in experimental group (P<0.05). ANOVA showed:the within-subjects, between-subjects and the interaction effects between two groups were statistically significant (P<0.05). Further pairwise comparisons in each group at four time points showed:the scores in later time point were lower than the former one, the difference was statistically significant (P<0.008).2. Sleep Quality. At four time points, the total score and each dimensions’ score of PSQI in experimental group were all lower than that in control group (P<0.05). ANOVA showed: the within-subjects effects, between-subjects effects and the interaction effects of the total score and score of each dimension were statistically significant (P<0.05). Further pairwise comparisons in each group at four time points showed:in the experimental group, the total score and score of subjective sleep quality, sleep time and daytime dysfunction dimensions in later time point were lower than the former one. In the control group, only the total score in later time point were lower than the former one, the differences were statistically significant (P<0.008).3. Daytime Fatigue. After intervention, the score of FFS in experimental group at eighth week, four weeks pro-intervention were lower than the same time point in control group, with significant differences (P<0.05). ANOVA showed:the within-subjects effects, between-subjects effects and the interaction effects between two groups were statistically significant (P<0.05). Further pairwise comparisons in each group at four time points showed:the scores in later time point were lower than the former one, the difference was statistically significant (P<0.05)4. Quality of Life. After intervention, the score of MLHFQ in experimental group at eighth weeks, four weeks pro-intervention were lower than the same time point in control group, with significant difference (P<0.05). ANOVA showed:the within-subjects effects, between-subjects effects and the interaction effects were statistically significant (P<0.05). Further pairwise comparisons indicated that: in both groups, score at eighth week, four weeks pro-intervention were lower than that before intervention (P<0.008), but the score at eighth week and four weeks pro-intervention were of no significant difference (P>0.008).5. Burden of Caregiver. After intervention, the score of DOBI in experimental group at eighth week, four weeks pro-intervention were lower than the same time point in control group (P<0.05). ANOVA showed: the within-subjects effects, between-subjects effects and the interaction effects between two groups were statistically significant (P<0.05). Further comparing in each group indicated that: the score at eighth week, four weeks pro-intervention were lower than that before intervention (P<0.05), but the score at eighth week and four weeks pro-intervention were of no significant difference (P>0.05).6. Blood pressure and heart rate:the level of blood pressure and heart rate in both groups at eighth week and four weeks pro-intervention were lower than that before intervention(P<0.05). But the level of blood pressure and heart rate between two groups at eighth week and four weeks pro-intervention were of no statistically significant (P>0.05).ConclusionsThe five-element music therapy combined with midnight-noon ebb-flow theory can relieve anxiety, daytime fatigue and burden of caregiver, improve sleep quality and the quality of life, Meanwhile, reduce blood pressure and heart rate among CHF patients with anxiety. This study can push the development of the time effect and standardization in five-element music therapy, furtherly promote the Traditional Chinese Medicine of time. It is deverse to explore further and widespread in hospitals and clinicals. |
PDF Full Text Request