The Status Of 701 Patients With Respiratory Tract Infection And The Usage Of Antimicrobial Agents

Objective:Through the investigation and analysis of the basic situation of hospitalized patients with respiratory tract infection, antimicrobial drug use basis, and the application of antibacterial drugs, understand the characteristics of the hospital antimicrobial drug use and unreasonable. Antibacterial drugs in order to strengthen management and provide certain guidance to promote reasonable use of antimicrobial drugs, for clinical doctors more valuable reference for the rational use of antimicrobial agents.Methods:Collected from January 2015 to June a level 2 grade a hospital was diagnosed with respiratory tract infection patients medical records, records of patients with gender, age, occupation, medical treatment charge payment basis, clinical diagnosis, disease, laboratory tests, imaging examination, whether used before and after admission to hospital antimicrobial, antibacterial drug category, drug name, change the situation, the combination and method such as data, statistics, analysis status quo and the use of antimicrobial agents in hospitalized patients with respiratory tract infection, further explore its reasonable and unreasonable use. Using Epidata statistical software for data processing.Results:1.Into the research materials of 701 cases, mean age 66.96 ±12.31 years old, in the majority with greater than or equal to 60 years of age, 77.60%; In terms of gender, male 43.79%, female 56.21%. In terms of career, give priority to with farmers, accounted for 77.60%; Medical expenses payment with rural cooperative medical care is given priority to, accounting for 77.18%.2.With underlying disease of 610 cases, accounting for 87.02%; And about 97.74% of the infection type the following respiratory tract infection, the most common for chronic obstructive pulmonary disease is chronic obstructive pulmonary disease, chronic pulmonary heart disease and chronic bronchitis,accounted for 30.53%, 23.81% and 30.53% respectively.3.Basis of antimicrobial usage: 82.31% of patients do the imaging examination, 100% of patients were the blood cell analysis; 18.69% of patients were the serum calcitonin original inspection; 20.54% of patients were the sputum bacterial culture, cultivate the results a total of 31 strains of pathogenic bacteria examination, including 29 gram stain negative bacillus strains.4.701 patients with respiratory tract infection in hospital antimicrobial drug utilization rate is 99.00%, according to the types of drugs, with the use of cephalosporins and head drug class frequency is higher, accounting for 32.60% and 31.03%, followed by beta lactam class/beta lactamase inhibitor, accounted for 19.71%; According to the name of the drug, to cefazolin sodium mino, piperacillin sodium/shu ba, cephalosporins for frequency of usage of sodium and sodium cefepime is higher, 29.9%, 18.3%, 17.1% and 18.3% respectively.5.Antimicrobial drug delivery way is given priority to with intravenous drip, accounted for 95.60%, accounted for only 4.40% of oral medicine.6.Patients during hospitalization to use an antibacterial drug is given priority to, accounting for 69.88%; Midway replacement of antimicrobial agents, a total of 215 times, including using replacement of ten times a day, use two days to replace have 28 times, use 3 days to replace 25 times, respectively, 4.65%, 13.02% and 11.63%, the rest of the replacement time is more than three days, accounting for 70.79%.7.Combined use of antimicrobial agents is given priority to with duplex, accounting for 6.34% of the total antimicrobial drug use, without the joint or more medications.Conclusions:1.701 cases of hospitalized patients with respiratory tract infection in the elderly, many associated with underlying diseases; Give priority to with farmers, their medical expenses payment is given priority to with rural cooperative medical care.2.Respiratory infectious diseases following respiratory infection is given priority to, common disease for chronic obstructive pulmonary disease, chronic cor pulmonale and chronic bronchitis.3.Clinicians use of antimicrobial agents based on mainly for patients with blood cell analysis and relevant imaging examination, less rapid serological detection and etiology examination.4.Antimicrobial drug use is given priority to with beta lactam type, cefepime by over-packaging mino sodium, sodium piperacillin/shu ba, cephalosporins for utilization of sodium and sodium cefepime is higher.5.Antimicrobial drug use is given priority to with alone, combination is less, and are two couplet medicines, without the joint and above combination.6.Antimicrobial drug use has some unreasonable phenomenon, embodied in: the antibacterial drug utilization rate is high, individual antimicrobial drug use is too concentrated, intravenous dosing ratio is too large, individual antimicrobial replacement frequency, mechanism of action, or the phenomenon such as antibacterial spectrum similar to that of antibacterial drug combination.