The Survival Analysis Of Critically Ill Patients Treated With Crrt At First Affiliated Hospital Of Guangxi Medical University In 2015

Objective:To observe the effects of continuous renal replacement therapy (CRRT) treated critically ill patients, and discuss the relationship between different dose and prognosis.Methods:Retrospectively analysis clinical data of 345 cases of critically ill patients, who stayed in our intensive care unit, including ICU, CCU, EICU, from January 2015 to December 2015. Observe survival at,3 days,7 days,28 days. Compare gender, age, underlying diseases, APACHE II before treatment, the number of organ failure, mechanical ventilation, blood lactate and oxygenation index, complications, CRRT treatment time, mood,dose, use of anticoagulants etc. Test the comparability of dose according to the results acquired, then discuss the relationship between different dose and prognosis.Results:At 3d and 7d, difference appeared on APACHEII score, the number of organ dysfunction, blood lactate levels, shock, severe infection, mechanical ventilation, secondary heart failure(P<0.05). At 28d, difference showed on age, despite of factors mentioned before(P<0.05). Nearly no difference in Sex, bad habits, underlying diseases, pretreatment oxygenation index, the average number of daily hours, anticoagulation(P>0.05). No difference in survival between the high dose group and the medium dose groups(P>0.05), but they were higher than the low dose group (P<0.05).Conclusions:Multiple factors affect prognosis, including APACHEII score, the number of organ dysfunction, blood lactate levels, shock, severe infection, mechanical ventilation, secondary heart failure after treatment. Dose more than 35 mL/(kg·h) can better help patients come through the acute phase of dysfunction. No use to raise dose more than 35. Hereafter, the treatment of primary disease control influence prognosis more.