Study Of Epidemiology And Repeated Infection Of Hand-foot-mouth Disease In Fuyang Anhui Province

Objective The epidemiology and etiology of hand-foot-mouth disease (HFMD) were analyzed in Fuyang from 2008 to 2014, so as to confirm the key region and groups of HFMD’s prevention and control. Meanwhile, the severe cases and repeated infection were surveyed.Methods The data was collected from the National Disease Surveillance Information Management System and the Surveillance Program of HFMD. Descriptive epidemiological method was used for statistical analysis. Nucleic acid of enterovirus (EV) genome was detected by Real-time PCR.Results 135345 HFMD cases were reported in Fuyang from 2008 to 2014, and the average incidence rate of HFMD was 242.57 per million.748 severe cases and 40 death cases were reported, the ratio of severe cases was 0.55% and the ratio of case fatality was 29.55 per million. The morbidity level presented rising trend on the whole, April to July is the peak of the HFMD. There were significant differences among the incidence in different districts. The number of male cases was more than the female ones. Children under 5 years old were more prone to HFMD. The age difference of severe patients was significant. The laboratory confirmed that 56.9% of HFMD cases were caused by EV71, and 8.7% were caused by CoxA16.511 repeated infection cases were reported in Fuyang in 2013, the ratio of repeated infection cases was 2.06%. The repeated infection ratio in three urban areas were higher than the other counties, and the peak incidence occurred from April to July. The ratio of repeated infection cases had significant differences in ages.Conclusion The incidence of HFMD was still in a high level in Fuyang, the morbidity presented rising trend on the whole, severe cases, death cases and repeated infection rate were also high. It has obvious seasonal and population distribution characteristics for HFMD in Fuyang. Children under 5 years old were more prone to HFMD. All the types cases of HFMD were mainly infected with EV71.