| Objective:By retrospective analyses on the general information,basic diseases,complex diseases,traditional Chinese medical(TCM)patterns and oral administration of Chinese materia medica,cardiac function classification,determination of echocardiography and cardiac function,as well aspro-brain natriuretic peptide of chronic heart failure patients,the paper discusses the correlation of rules of TCM patterns of chronic heart failure patients in Guangxi,so as to provide clinical data for the TCMtreatment in heart failure.Method:The information of 1,647 chronic heart failure patients from 7hospitals were collected in the research,including their general information,basic diseases,complex diseases,TCM patterns and oral administration of Chinese materia medica,cardiac function classification,determination of echocardiography and cardiac function,as well aspro-brain natriuretic peptide,which was analyzed retrospectively.Results:1.The chronic heart failure patients were at the age of 68.98 ± 13.06 in average,those at the age from 70 to 79 had the highest morbidity.Moreover,the morbidity of male patients was higher than that of female patients before the age of 60 and vice versa.2.Among 1,647 patients,those with coronary heart disease accounted for42.44%;with hypertensive heart diseaseaccounted for 17.61%;with hypertension accounted for 44.32%;with arrhythmia accounted for 32.73%;with community-acquired pneumoniaaccounted for 25.62%;with type-2 diabetesaccounted for 13.30%.Moreover,those with oral administration of Chinese materia medica accounted for 80.15% while those without that for19.85%,which had a significant difference(P<0.05).3.Among 1,647 patients,those with cardiac function Ⅲ,Ⅳ and Ⅱaccounted for 58.04%,33.94% and 8.02% respectively,and there were significant differences among the different levels of cardiac functional grading(P<0.05).Patients with cardiac function Ⅲ accounts for the largest proportion,and there was a statistical significance of cardiac functional grading among different ages(P<0.05).4.Among 1,647 patients,those withheart-lung Qi deficiency accounted for25.39%;with Qi deficiency and blood stasis accounted for 21.91%;with Qi-Yin deficiency accounted for 19.37%;with phlegmobstructing lung accounted for 17.12%;with edema due to Yang deficiency accounted for16.21%.5.There a correlation between hypertensive heart disease and chronic heart failure,mainly with the patterns of heart-lung Qi deficiency and Qi-Yin deficiency.There was not correlation between coronary heart disease and chronic heart failure6.Patients with different TCM patterns mainly suffered from cardiac functionⅢ.The proportion of patients suffering from cardiac function Ⅱwiththpattern of Qi deficiency and blood stasis,heart-lung Qi deficiency(equaling to phlegm obstructing lung),Qi-Yin deficiency,as well as edema due to Yang deficiency respectively decreased successively.The proportion of those suffering from cardiac function Ⅲ with pattern of heart-lung Qi deficiency,Qi deficiency and blood stasis,Qi-Yin deficiency,phlegm obstructing lung,as well as edema due to Yang deficiency respectively decreased successively.The proportion of those suffering from cardiac functionⅣ with pattern of edema due to Yang deficiency,heart-lung Qi deficiency,phlegm obstructing lung,Qi-Yin deficiency,as well as Qi deficiency and blood stasis respectively decreased successively.It was verified that there was a statistical significance among the cardiac functional grading with different TCM patterns P<0.05.7.The level of left ventricular ejection fraction(LVEF)in the left ventricular of chronic heart failure patients with the pattern of Qi deficiency and blood stasis,heart-lung Qi deficiency,Qi-Yin deficiency,phlegm obstructing lung,as well as edema due to Yang deficiency respectively decreased successively.There was a significant difference between the patterns of Qi deficiency and blood stasis,edema due to Yang deficiency and the patterns of Qi-Yin deficiency,heart-lung Qi deficiency as well as phlegm obstructing lung(P<0.05).The proportion of left ventricular end-diastolic dimension(LVEDD)patients with the pattern of edema due to Yang deficiency,phlegm obstructing lung,Qi-Yin deficiency,heart-lung Qi deficiency,as well as Qi deficiency and blood stasisrespectively decreased successively.There was a significant difference between the pattern of Qi deficiency and blood stasis and the patterns of Qi-Yin deficiency,heart-lung Qi deficiency,phlegm obstructing lung as well as edema due to Yang deficiency(P<0.05).The proportion of left ventricular end-systolic dimension(LVESD)patients with the pattern of edema due to Yang deficiency,phlegm obstructing lung,Qi-Yin deficiency,Qi deficiency and blood stasis,as well as heart-lung Qi deficiencyrespectively decreased successively.There was a significant difference between the pattern of edema due to Yang deficiencyand the patterns of Qi-Yin deficiency,heart-lung Qi deficiency,phlegm obstructing lungas well as Qi deficiency and blood stasis(P<0.05).8.The level of NT-pro BNP in the pattern of Yang deficiency and blood stasis,phlegm obstructing lung,Qi-Yin deficiency,heart-lung Qi deficiency,as well as Qi deficiency and blood stasis respectively decreased successively,which had statistical significances(P>0.05).Conclusion:1.The senior at the age between 70 and 79 accounted for the largest proportion among chronic heart failure patients,and the morbidity of female patients will increase as their ages grows.2.Both coronary heart disease and hypertensive heart disease are the underlying diseases of the chronic heart failure.In addition,the complex diseases,including hypertension,arrhythmia,community-acquired pneumonia and type-2 diabetes,have significant effects on the chronic heart failure as well.3.Most chronic heart failure patients were willing to accept the treatment with Chinese materia medica,which showed a favorablecompliance.There was no significant difference of the compliance for oral administration between male patients and female patients.4.TCM Clinical Syndromes and Factors of Chronic Cardiac Failure in Partial Regions of Guangxi mainly with the pattern of heart-lung Qi deficiency.Hypertensive heart disease were mainly with the pattern of Qi-Yin deficiency and heart-lung Qi deficiency.There was a correlation between hypertensive heart disease and TCM patterns,while no relations between coronary heart disease and TCM patterns.5.Chronic heart failure patients mainly suffered from cardiac function Ⅲ,which had a correlation with TCM patterns.Furthermore,patients suffered from cardiac function Ⅱ mainly with the pattern of Qi deficiency and blood stasis;cardiac function Ⅲ mainly with the pattern of heart-lung Qi deficiency;cardiac function Ⅳ mainly with the pattern of edema due to Yang deficiency.The heart failure with the pattern of edema due to Yang deficiency was the most severe.6.There was a correlation between left ventricular function and TCM patterns.The decreasing level of LVEF in the left ventricular and increasing level of LVEDD and LVESD were mainly with the pattern of edema due to Tang deficiency.7.There was significant correlation between NT-pro BNP and TCM patterns,the decreasing level of NT-pro BNP were mainly with the pattern of edema due to Tang deficiency. |
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