The Effect Of Acupuncture Intervention To Phlegmy Wet Pixu For Metabolic Syndrome Glycometabolism

Objective: Metabolic syndrome(MS)is disturbance of protein,fat,carbohydrates metabolic abnormalities which includes obesity,diabetes,blood lipid disorder with low high-density lipoprotein cholesterol(HDL-C)or high triglycerides(TG)and high blood pressure.And incidence of MS is increasing with improved living standard.Clinically at the primary stage of disease,there is non-drug therapy including low-salt low-fat diet and high fiber foods.Moreover moderate exercise contributes to induction of LDI and increase of HDI.If there is obvious symptom,symptomatic treatment is necessary.However,long-term drug therapy would impair liver and kidney and there are obvious other side effects.In Chinese traditional medicine,MS is caused by eating disorders,modern imbalance and lack of innate endowment.This qi,this virtual by qi and yang deficiency is the basic pathogenesis,wet phlegm and blood stasis is surface phenomenon,liver,spleen and kidney are related to the disease.Especially the spleen(qi)is key factors of the disease.Removing wet and blood stasis are treatment principle clinically.Acupuncture of traditional Chinese medicine can make up for the Deficiencies and limitations on clinical treatment of Modern medicine.The aim of the present study is to identify the regulation of electroacupuncture on glycometabolism in patients with MS and explore the mechanism.Methods: 82 patients with MS are enrolled as the inclusion criteria and are separated into normal control group with 41 and experimental group with41 randomly.There are only conventional medication therapy in normal control group,such as Glipizide Controlled Release Tablets 5mg per tablet,1tablets each time,1 times/day with diabetics before breakfast;Felodipine Sustained Release Tablets 5mg per tablet,1 tablets each time,1 times/day with hypertensive patients before breakfast;Simvastatin Tablets 20 mg per tablet,1tablets each time,1 times/day with diabetics dyslipidemia patients after dinner.Patients in experimental group were acupunctured zhongwan(RN12),guanyuan(RN4),yinlingquan(SP9),zusanli(ST36),sanyinjiao(SP6),taichong(LR3),taibai(SP3),taixi(KI3),ganshu(BL18),pishu(BL20),weishu(BL21),shenshu(BL23)on the basis of medication.Twelve meridians are bilateral and we take 0.5-1.5 inches filiform needle Hua tuo card,acupuncture two minutes when get the needle feeling,connect G6850-2Aelectric acupuncture apparatus dilatational wave,Needles were kept in muscles for 20 minutes on sanyinjiao(SP6),zusanli(ST36),guanyuan(RN4),zhongwan(RN12),once a day for 10 times as one course.There are three courses totally.Measure and record the fasting blood-glucose,2h postprandial blood glucose,fasting glucose,insulin resistance index,body mass index,systolic pressure and diastolic pressure before and after treatment in both groups.T-test and variance analysis were used to compare the changes before and after treatment.All the analyses were performed in SPSS 13.0.Result:1 basic dataBefore the treatment,Age(Age),the course team(Process),sex,body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),fasting blood glucose(FBG),2h postprandial blood glucose(2hPG),fasting insulin(Fins)and insulin resistance index(HOMA IR)in both groups had no statistical significance(P>0.05).2 indicator to compare2.1 There is no statistical significance in BMI in the control group before and after treatment(P>0.05).BMI in the experimental group is significantly smaller after acupuncture treatment(P<0.05).2.2 There is no statistical significance in SBP and DBP in the control group before and after treatment(P>0.05).DBP is significantly different in the experimental group before and after acupuncture treatment(P<0.01).2.3 There is no statistical significance in FBG,2hPG,Fins and HOMA-IR in the control group before and after treatment(P>0.05).FBG,2hPG,Fins andHOMA-IR are significantly different in the experimental group before and after acupuncture treatment(P<0.01).3 effect comparisonApplication of rank and inspection is the overall efficacy of the two groups after treatment,Uc = 1.349<2.58,according to the alpha = 0.05 standard of hypothesis test,P>0.05,two groups of curative effect compared with no statistical significance.Conclusion:1 Acupuncture with drug therapy in patients with metabolic syndrome can i basic drug treatment effect;2 Acupuncture with drug therapy in patients with metabolic syndrome can effectively adjust the body mass index(BMI);3 Acupuncture with drug therapy in patients with metabolic syndrome can effectively adjust the level of blood pressure;4 Acupuncture with drug therapy in patients with metabolic syndrome can effectively reduce the fasting plasma glucose,postprandial 2h blood glucose,fasting insulin and insulin resistance index.