| Objective:To observe the clinical efficacy and safety of acupuncture combined with medicine in the treatment of spleen deficiency and phlegm dampness polycystic ovary syndrome with hyperandrogenemia,in order to provide new treatment ideas and basis for the personalized diagnosis and treatment of polycystic ovary syndrome with hyperandrogenemia and the prevention of long-term complications.Methods:According to the order of enrollment,64 patients with splenic deficiency and phlegm dampness type PCOS were recruited from November2020 to December 2021 who seek medical advice the gynaecology outpatient clinic of the First Affiliated Hospital of Heilongjiang University of Chinese medicine,and they were randomly divided into experimental group(n=32)and control group(n=32).32 cases in the experimental group were treated with acupuncture point stimulation combined with TCM Decoction,while 32 cases in the control group were treated with TCM Decoction,and there were 3months of treatment.Changes in TCM syndrome total scores,gonadal hormone level,testosterone levels,and other safely indicators were compared before and after treatment in the tow groups.All the results were statistically analyzed.with relevant laboratory tests and clinical signs scores.Result:1.Comparison of combined efficacy: After the comprehensive efficacy of the two groups,the effective rate of the experimental group was 86.67%,and the efficiency of the control group was 63.33%,and the difference was statistically significant(P=0.016<0.05)after the order test,indicating that the comprehensive efficacy of the experimental group was better than that of the control group.2.Comparison of TCM Syndrome Points: After 3 months of treatment,the TCM syndrome scores of the two groups improved compared with before treatment,and the difference was significantly significant(P<0.01),and the improvement of TCM syndrome in the experimental group was better than that in the control group(P<0.05).3.Comparison of serum gonadal hormone: There was no significant improvement before and after FSH treatment in the two groups,and the difference was not statistically significant(P>0.05);the LH and LH/FSH in both groups were significantly improved(P<0.05),and the efficacy of down-regulating LH in the experimental group was obvious and there was a significant difference(P<0.01),which was better than that of the control group.4.Comparison of androgens levels(T,AND,DHEAS,SHBG,FAI):After treatment,T,AND,DHEAS,SHBG,FAI and pre-treatment were all improved,and the differences were significant(P<0.01),and the experimental group improved T,AND,DHEAS,SHBG and FAI better than the control group,and the differences were statistically significant(P<0.05).5.BMI: After treatment,the BMI of the patients in both groups was significantly improved(P<0.05),and the experimental group improved significantly compared with the control group(P<0.05).6.WHR: After treatment,the WHR of the two groups of patients was improved(P<0.05),and the experimental group improved significantly compared with the control group(P<0.05).7.m F-G score: The differences in m F-G score between the two groups were not statistically significant(P = 0.212>0.05).8.Rosendield score: The improvement of acne in the experimental group after treatment was better than that in the control group(P<0.05);the difference between the control group was not statistically significant(P=0.112>0.05).Conclusions:1.Acupuncture combined with invigorating spleen and eliminating phlegm prescription can reduce the TCM syndrome of Splenic Deficiency phlegm dampness type pcos-ha subjects,and improve the clinical discomfort symptoms of patients has a positive significance,and the efficacy of acupuncture to pick up points is worth confirming.2.Acupuncture combined with the treatment of spleen deficiency sputum wet PCOS-HA,in the reduction of BMI,WHR effect is particularly significant,acupuncture can enhance the spleen deficiency sputum wet PCOS-HA patients clinical efficacy,no obvious side effects,effective and convenient,worth promoting. |
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