Research On Correlation Between The Change Of Cognitive Function After The Ischemic Stroke And TCM Syndrome

Objective:To discuss the features of cognitive function impairment in the recovery stage and sequelae stage for the patient who suffers from the Ischemic Stroke and the relation between these futures and TCM Syndrome.Object & Method:select 120 appropriate patients in the recovery stage and sequelae stage of Ischemic Stroke as the cases, and collect the general data, MoCA, ADL, MESSS, TCM Syndrome factors as well as HAMD and Hachincki ischemic integral scale. Among them, with ’MoCA scale scores will be divided into cognitive dysfunction group (MoCA<26 points) and cognitively normal group (MoCA score ≥26).By the statistics and analysis, it is to discuss the features of nerves, daily living abilities and cognitive function impairment and the relation between these futures and TCM Syndrome for the patients who are in the recovery and sequelae stages of Ischemic Stroke. SPSS 18.0 is adopted to conduct data analysis.Results:1. The comparison of illness group with normal group for the score conditions in all cognitive fields of MoCA:there is statistical significance for the score differences in the cognitive fields, namely visual space and executive function, attention, language, delayed memory and orientation (P<0.05), which states the five cognitive functions has been damaged.2. The comparison of correlation among ADL, MESSS and MoCA:the change of cognitive function is closely relevant to MESSS and ADL. The more damages that the neurological function suffers from, the lower daily living ability the patient has and more serious the cognitive dysfunction is.3. The analysis on the signal factor of cognitive function and TCM Syndrome:there is no distributional difference between the two groups with respect to endogenous fire, phlegm-damp, deficiency of vital energy, deficiency of yin and liver vacuity, while the blood stasis and kidney deficiency have the statistical significance in terms of distribution between the groups (P<0.05). For the blood stasis of the two group, OR=2.723 and 95% of CI is (1.032,7.185), while OR=3.107 and 95% of CI is (1.174,8.224) in the aspect of kidney deficiency, and it explains the blood stasis and kidney deficiency are the main TCM factors to affect the cognitive function.4. The binary logistic regression analysis on multiple factors of MoCA for the patients with Ischemic Stroke:it is found that the blood stasis and kidney deficiency are the main risk factors for the cognitive dysfunction (P<0.05).5. The multi-factor analysis on all cognitive fields of MoCA scale for the patient in the illness group:it is shown that whether the visual space and executive force decrease is affected by the deficiency of vital energy and deficiency of yin in the TCM Syndrome; whether the attention decreases is affected by the deficiency of yin; whether the delayed memory decreases is affected by deficiency of vital energy; and whether the language and orientation decrease is not affected by TCM Syndrome.Conclusion:The patients who suffer from Ischemic Stroke have the cognitive dysfunction with different degrees whose main manifestations include the damage in five cognitive fields, namely visual space and executive function, attention, language, delayed memory and orientation. The change of cognitive function is closely related to MESSS and ADL. The more damages that the neurological function suffers from, the lower daily living ability the patient has and more serious the cognitive dysfunction is. The distribution situation of TCM Syndrome for the patients with Ischemic Stroke:the syndromes of phlegm-damp and blood stasis are often seen as the real syndromes, while in the deficiency syndrome aspect, it is often seen by deficiency of vital energy and kidney deficiency. The signal-factor and multi-factor analyses on cognitive function and TCM Syndrome both show the blood stasis and kidney deficiency may be the main TCM factors to affect the cognitive function, and the further anal/sis states that whether the cognitive fields, visual space and executive force, decrease is affected by the deficiency of vital energy and deficiency of yin in the TCM Syndrome; whether the attention decreases is affected by the deficiency of yin; whether the delayed memory decreases is affected by deficiency of vital energy.