Correlation Of The Syndrome In Acute Cerebral Infarction With CRP And The MRS One Years Later

Objective:To investigate the correlation between CRP level and acute cerebral infarction, discuss the correlation of the syndrome in acute cerebral infarction with CRP,NIHSS score and the mRS one years later.Provide objective basis of using traditional Chinese Medicine to affect CRP and decrease the degree of nerve damage, to provide a new reference for the prognosis of cerebral infarction and the prediction of the disability degree, prompt intervention of related factors as soon as possible to reduce the degree of disability and disability rate of the disease.Methods:Formulate normative research table,choose eighty hospitalized patients with acute cerebral infarction, on admission, evaluate the degree of nerve and classify the syndrome,determine the level of CRP. One years later follow up the patients with cerebral infarction,record the occurrence of cardiovascular events and mRS.Collect 20 people matched in age, sex and not suffering from cardiovascular and cerebrovascular disease in physical examination population as the control group, determine their CRP levels, and compared with the cerebral infarction group.Results:(1)the syndrome’ occurrence frequency of the subjects on admission is phlegm-syndrome(62)>blood-stasis-syndrome(60)>wind-syndrome(52)>fire-heat-syndrome(2 1)>qi-deficiency-syndrome(8)>syndrome of hyperactivity of yang due to yin deficiency(1).All the syndromes were mainly mild.(2)CRP of cerebral infarction group were significantly higher than the normal group, the difference was statistically significant,the level of CRP in the acute phase is related to the digree of wind syndrome and if the wind syndrome was established or not.On admission when the heat syndrome was established,the NIHSS score of acute cerebral infarction was higher than that of the syndrome when the heat syndrome was not established, but when the phlegm syndrome was established it was lower than that of the syndrome when the phlegm syndrome was not established. There is a certain correlation between NIHSS score on admission and fire-heat syndrome integral, Qi deficiency syndrome integral,fire-heat syndrome degree, phlegm syndrome degree and fire-heat syndrome was established or not, phlegm syndrome was established or not.(3)1 years later the onset of mRS have a certain degree of correlation with the NIHSS score on admission, wind syndrome integral of acute phase, the establishment of wind syndrome or not and the degree of wind syndrome.Conclusion:(1)Phlegm syndrome, blood stasis syndrome and wind syndrome are the main syndrome factors in acute phase of cerebral infarction.(2)The level of CRP is closely related to the acute cerebral infarction. There is a certain correlation between CRP level and wind syndrome in the acute stage. The use of traditional Chinese medicine intervention CRP level to prevent cerebral infarction has objective basis.(3) The degree of disability can be predicted through the acute phase of cerebral infarction syndrome and NIHSS score.For high-risk patients use the traditional Chinese medicine soon as possible, and prompt that we should make treatment according to syndrome differentiation of TCM and using traditional Chinese medicine as early as possible in order to reduce the disability rate and the degree of disability of cerebral infarction.