| Objective:Using clinical epidemiology and statistical methods summarize the characteristics of children with chronic cough disease, TCM common syndromes and distribution, to provide a reference for the optimization of the disease syndrome differentiation program.Methods:This issue covers the literature research and clinical epidemiology research. The former one is to formulate the investigation Questionnaire of Syndrome of Children with chronic coughs disease by retrieving 2004 to 2014 “China National Knowledge Network(CNKI)†" Medical Network" target literature Summed up in children with chronic cough TCM syndrome characteristics. The latter one is by means of questionnaire survey to collect the clinical data of children with chronic cough and by means of the statistical software SPSS18.0 to establish the data base for the information and by means of the statistical methods such as Frequency Analysis, Cluster Analysis to Explore law and TCM Syndrome distribution characteristics of Children with chronic coughs disease.Results:Literature add up 648,effective literature total 46, The cumulative number of cases is 3648 which involving studying cases of children with chronic cough TCM syndromes, Summary of TCM syndromes of 28 species, Of which relates to viscera there are lung, spleen, kidney, liver, in order to lung-based. Main pathogenic factors are wind, heat, phlegm, indigestion. A large proportion of the empirical disease, followed deficiency, the smallest proportion of the actual situation mixed card. Clinical epidemiological studies: In effective 170 cases, the incidence of women slightly more than men. In this study of children with chronic cough,the age of onset is between 3 ~ 12 years old, the average age is 5.11± 2.01 years; In duration is between 1 month to 5 years, duration of 70% children is from 1 month to 2 month; The onset of the season in the autumn and winter seasons,accounting for 63.71%. In the research, cough symptoms is first, involving 52 kinds of secondary symptoms, including the tongue and pulse. The number of clinic symptoms whose percentage of frequency is more than 30% is 21. There are 4 main symptoms of whose ratio of frequency is more than 30%. Starting from the one in highest proportion to the one in lowest, they are separately strong cough sound, cough frequently in day, excess of phlegm, white phlegm. It relates to viscera there are lung, spleen, liver, in order to lung-based. Main pathogenic factors are wind, heat, phlegm, indigestion. After cluster analysis, the common syndromes of chronic cough can be categorized into 7 types: Phlegm resistance syndrome(65 cases, accounting for 38.24%), phlegm heat obstructing lung syndrome(43 cases, accounting for 25.29%), wind attacking lung syndrome(5 cases, accounting for 14.71%), deficiency of both Qi and Yin & wind attacking lung syndrome(18 cases, 10.59%), deficiency of Lung and spleen & dyspepsia resistance syndrome(7 cases, accounting for 4.12%), deficiency of Lung and spleen & wind attacking lung syndrome(6 cases, accounting for 3.53%), Disharmony and anger & certificate(6 cases, accounting for 3.53%), Liver and stomach Discord & liver fire attacking lung syndrome(6 cases, accounting for 3.53%).Conclusion:1 The incidence of chronic cough in children is closely associated with lung and spleen and liver three viscera. "The wind evil and phlegm and indigestion" plays an important role in the pathogenesis of the disease. The basic pathogenesis is feiqishangni and Xushijiaza is one of the characteristics of pathogenesis.2 Phlegm resistance syndrome and phlegm heat obstructing the lung syndrome account for a large proportion, deficiency syndrome is less. The complex syndromes account for a considerable proportion(21.7%). This phenomenon is objective. It should cause enough attention.3 The theorem of Cluster analysis can more reasonably reflect the clinical syndrome type. It shows that the research method is feasible.4 Under the present circumstances, to carry out a large sample and multi-center study has practical significance. It shows that this research has some application value.5 There is a concordance between the result of the literature research and the authority. It shows that the result of the literature research can provide a reliable basis for the clinical research. |