Research On Syndromes Elements Characteristic And Syndromes Standard Of "Cough"

Objective: To explore the distribution, combination and the essence of syndrome's elements of coughMethods:1. Literature research: To systems review literature existed in the past and recent years and statistically analyze the cough-related documents in the past decade,to recognize the denotation ,etiological factors, pathogenesis ,syndromes distributions and research progression of cough . 2.Clinical and experimental research: Use the methods of the clinical investigation combining with diagnosis measurement of Traditional Chinese medicine (TCM) and multiple statistical analysis to research the common syndrome's elements of 1095 cough patients in FUZHOU. To approach the rules of its distribution and combination ,and the important symptoms which contribute to diagnosis statistically as well. 3.Empirical study :To approach the relationship between the detection indexes such as haemocyte, blood-fat, blood glucose ,which commonly used in clinics, and phlegm and heat syndrome's elements by analyze these indexes.Results: 1. Literature research: By completely reviewing all the past literatures ,to know the descriptions of the significance and denotation of cough in the past and recent years are ambiguous, and the classifying methods aren't identical. There exist many dissensions of whether cough has to be regarded as a symptom or a disease, and in the differentiation of symptoms and signs for classification of syndrome, which mostly based on clinical reports and individual experience. Or to research cough by the point of view of the "disease" in modern medicine, and classify syndromes stably according to the pathology characteristic of the disease, these methods neglect the integer thinking of differentiation of syndromes of TCM, and also couldn't meet the clinical need. Differentiation of syndrome's elements accords with the Gestalt Principle of System Theory, and could reflect proximately the characters of cough.2. Clinical research: Through clinical research, using the method of counting-diagnosis of TCM, to research the distribution, combination of the syndrome's elements of cough. The result:(1) Symptoms and physical signs: the most symptoms and physical signs of cough is phlegm and heat.(2) Variable clustering analysis: the common elements of syndrome of cough : exogenous wind-evil ,deficiency of Qi, cold, deficiency of Yang, insufficiency of yang, phlegm , heat and exterior. To do the principal component analysis to every elements of syndrome, find out the cardinal symptoms, subcardinal ones.(3) Distribution regular of syndrome's elements : the characteristic syndrome's element phlegm and the position syndrome's element Lung appear in every phase of the disease, heat appears mostly in all course of the disease; when the course is long the frequency of the appearance of deficiency of Qi is the highest, and the spleen , the kidney and the heart are effected. When it is short the position syndrome's element exterior appears mostly. The patient is younger, the excess syndrome's elements such as heat appear more frequently. Concerning child the food retention and interior stirring-up of wind usually appear , whose stomach, small intestine, and liver are effected. The patient is older ,the syndrome's elements of simultaneous deficiency and excess appear more frequently, such as deficiency of Qi or Yang combining with phlegm, heat, cold, or retention of fluid ,whose lung, spleen and kidney are effected ,and the heart would be effected at last.(4) Combination regular of elements of syndrome: Phlegm and lung is the pathology basement of cough, the exterior evil is the main motivation, and heat is in the primary place.3.Clinical experiment research: the result shows: There exists haemocyte , lipid metabolism and glycometabolic abnormity in the patients of phlegm and heat cough, but there's no significant deviation between these two groups.Conclusions: 1.Cough is the common even the primary symptom of lung diseases, so it's not suitable to regard "cough" as a name of a disease. But it could be called as "cough species" according to using the primary symptom cough as a core to classify lung diseases. 2. according to variable clustering analysis, the common syndrome's elements of cough are : exogenous wind-evil ,deficiency of Qi, cold, deficiency of Yang, insufficiency of yang, phlegm , heat and exterior. 3. The distribution and combination of syndrome's elements are very complicated, the combination of several syndrome's elements is major, lung and phlegm are present in every phase of cough. The disease position and characteristic is different between the groups of different courses and different ages. 4. The indexes could be used as auxiliary examination methods, without being regarded as the characteristic indexes of the syndrome's elements of phlegm and heat. So it can't be used alone to diagnose a syndrome in the clinic, several-factors treating is the new method for the research of syndrome's elements.