The Neuropsychological Feature Of Mild Cognitive Impairment In Elderly Surgical Patients

Objective To investigate the neuropsychological feature of mild cognitive impairment in elderly surgical patients.Materials and Methods All the subjects aged form 60 to 79 years old were recruited from the Affiliated Union Hospital of Fujian Medical University. A total of 15 elderly surgical patients with a MCI, 27 elderly surgical patients with non-a MCI and 19 healthy elder people as normal control were selected.Each individual underwent the neuropsychological tests, including Montreal cognitive assessment(Mo CA), Auditory verbal learning test(AVLT), Clinical Dementia Rating(CDR), General Deterioration Scale(GDS), The Barthel index of(ADL)and Hamilton Depression Rating Scale(HAMD).Then using the Chi square test, Fisher exact test, Single factor analysis of variance, Non parametric test ’Kruskal Wallis test’, Bonferroni method and other statistical methods with the SPSS Chinese version 19 statistical software to analysis neuropsychological characteristics between 3 groups of subjects.Results The a MCI group, non-a MCI group and normal cognitive function group in the Mo CA project showed statistically significant differences except in language fluency. The scores of Auditory verbal learning test(AVLT) were statistically significant differences. Comparison between any two parameters between 3 groups of Mo CA: 1. a MCI group compared with normal cognitive function group: the difference between two groups in Mo CA total score, visual spatial and executive function, naming, attention, language repetition, abstraction, memory and orientation was statistically significant. The difference was not statistically significant in verbal fluency, indicated the verbal fluency was relative retained.2. Comparison of non-a MCI group with normal cognitive function group: in addition to language fluency, the differences of attention and orientation was not statistically significant(test value=1.0092, 0.659; P=0.315, 0.417; P>0.05). The differences of Mo CA total score, visual spatial and executive function, naming, language repetition, abstraction and delayed recall were statistically significant(P<0.05).3. aMCI group compared with non-aMCI group: the difference between the two groups in directional force was statistically significant(P<0.05).Comparison between any two parameters between 3 groups of AVLT :1. a MCI group compared with normal cognitive function group: the differences be-tween the two groups in of the recognition scores were statistical significance(P<0.05).2. Comparison of non-aMCI group with normal cognitive function group: The differences of AVLT-1, AVLT-4, AVLT-5, and AVLT-T were statistical significance(P<0.05) except AVLT-2, AVLT-3, AVLT-I, recognition and AVLT-E(P=0.429, 0.190, 0.057, 0.074, 0.072).3. aMCI group compared with non-aMCI group, there were no statistically significant different between two groups’ scores of recognition and AVLT-E(P=0.095, 0.217). The scores were significantly different in AVLT-1, AVLT-2, AVLT-3, AVLT-I, AVLT-4, AVLT-5 and AVLT-T(P<0.05).Conclusions The patients of a MCI Group and non-a MCI group show multiple cognitive domains of damage. In the Mo CA project only show the orientation difference was statistically significant, Mo CA for screening of MCI patients is more ideal, but did not reflect the characteristics of the changes of a MCI and non-a MCI. The important clinical feature of MCI is the memory impairment and the memory impairment has certain plasticity.