Correlations Between Dental Caries And Salivary Flow Rate,pH Value,Buffer Capacity In Xerostomia Patients

Objective:To investigate the incidence of dental caries and salivary character in patients with xerostomia, and analyze the relationship between them, explore the effect of salivary changes in patients with dry mouth on caries development, provide reference for future clinical prevention and control countermeasures of dental caries in xerostomia patients.Methods:101 xerostomia patients were collected as research objects, equal amounts of healthy persons with matching gender and age without systemic diseases in the physical examination center as control group. Oral examination and saliva analysis were conducted and then analyzed the difference in caries prevalence rate,decayed-missing-filled teeth(DMFT) value, unstimulating whole salivary(UWS) flow rate, stimulating whole salivary(SWS) flow rate,UWS p H value and buffer capacity between two groups. And the relativity between the DMFT index and properties of saliva in patients with xerostomia were explored as well. SPSS 20.0 software was used for statistical analysis of detection results.Results:1. Xerostomia group caries prevalence rate was significantly higher than that of the control group(P<0.001). DMFT index was significantly higher than that of the control group(P<0.05);2. Decrease of UWS was the main performance in xerostomia group. The UWS,SWS, salivary p H value and buffering capacity in Xerostomia were significantly lower than those of control group and the difference was statistically significant(P<0.01);3. Obvious negative correlation were appeared between the following and the DMFT index in xerostomia group: the p H value of the saliva(r=-0.66, P=0.001)and the buffer capacity(r=-0.301, P=0.002).Conclusions:1. Xerostomia patients are the high-risk population of suffering the caries with more serious degree;2. There is no linear correlation between decreased salivary flow rate and the severity of caries in xerostomia patients, only a weak correlation between flow rate and high caries prevalence rate;3. The reduction of buffer capacity and saliva p H valuer may be a key factor for the severity of dental caries in patients with xerostomia.