Research On The Synthesis Of AgBr Nanoparticles And Its Antimicrobial Activity

Antibacterial agent can be divided into inorganic antibacterial agent, organic antibacterial agent, natural antibacterial agent and polymer antibacterial agent.Inorganic antibacterial agent, compared with other antibacterial agent, has many advantages such as long service life, no drug resistance, non-toxic side effects, slow release, high temperature resistance, and so on. Silver ions have strong antibacterial ability, its antibacterial mechanism mainly is contact reaction mechanism.Photocatalytic antibacterial agent is a class of inorganic antibacterial agent, and titanium dioxide is a common one. Due to titanium dioxide has high band gap, it only absorbs uv light under 400 nm, limiting the utilization of the sunlight. Silver bromide can slowly release silver ions, performing antibacterial function. Silver bromide is also an important photocatalyst for photocatalytic antibacterial. Silver bromide has lower band gap, able use energy from the part of the visible light to perform photocatalytic antibacterial function.In this paper, silver bromide particles with different sizes are synthesized through a friendly, green, simple method. The minimum bactericidal concentration(MBC),minimum inhibitory concentration(MIC), enzyme activity, bacteria live/dead fluorescence dyeing are studied to investigate the antibacterial ability of silver bromide nanoparticles. MIC of silver bromide nanoparticles is 10 ppb, minimum inhibitory concentration is 400 ppb. The Ag Br nanoparticles show excellent antibacterial ability.Silver bromide nanoparticles surface was reduced to get silver bromide/silver nanoparticles. The particle size decreases after further reduction. Due to the silver bromide/silver nanoparticles size is small, it has a lower MBC. Because the silver occurs on the surface of bromide/silver nanoparticles, the released silver ions is less, the MIC is 750 ppb. The surface silver possesses the local surface plasmon resonance(LSPR) effect, improving the particle to visible light absorption and optical electron transfer, exhibits better photocatalytic antibacterial ability. The as synthesized nanoparticles can be doped with some spontaneous film-forming materials, making an antibacterial spray, which is convenient and easy to use.