Effect Of Shugan Bushen Recipe On Liver Stagnation And Kidney Deficiency Type In Patients With Hyperprolactinemia

Objective: To investigate the effects of this issue by Shugan Bushen recipe on liver stagnation and kidney deficiency patients with hyperprolactinemia, evaluation of liver and kidney compound on hyperprolactinemia kidney liver depression symptom improvement, for the screening of more safe and effective treatment of hyperprolactinemia Compound provide clinical evidence, hoping to lay the foundation for further exploration of the researchers.Methods: By cluster sampling, rigorous subjects included 60 cases, according to shuffle the list divided into liver and kidney compound group, bromocriptine group of 30 cases,Course of the study, one case of anaphylaxis bromocriptine group terminated observation, so the actual number of people earning group, the treatment group 30 cases, 29 cases in the control group. Serum prolactin levels were observed before and after treatment and TCM syndrome to improve the situation of the two treatment methods of clinical observation, data recording, statistical analysis.Results: The total effect of the difference was not statistically significant(P> 0.05),that is no difference in overall efficacy of traditional Chinese medicine and bromocriptine, efficiency were 83.33%、82.76%; two therapy in improving TCM syndrome was statistically significant(P<0.05),and Shugan Bushen therapy do well in improving the symptoms of liver depression and kidney effective, efficiency were 53.33%、31.03%; Shugan Bushen therapy for improving backache and soft knees, irritability, breast swelling pain, dizziness, forgetfulness or tinnitus symptoms than bromocriptine, the disparity was statistically significant(P <0.05); two in improving menstruation, menstrual wrong, galactorrhea, infertility, menstrual period pain, loss of libido symptoms terms of efficacy rather, disparity was no statistical significance(P> 0.05); compare the serum PRL values within the group, the disparity was statistically significant(P<0.05), The disparity was not statistically significant between both groups after the treatment( P> 0.05); treatment group safety index test showed no abnormal clinical safety studies showed that the drug application security.Conclusion: liver and kidney deficiency< sym① ptoms compound to improve the efficacy of liver depression is superior hyperprolactinemia bromocriptine; ②Shugan Bushen compound can reduce serum prolactin levels,the same efficacy with bromocriptine,similar overall efficacy to hormone therapy(26.72ng/ml<PRL<100ng/ml); ③Shugan Bushen compound is safe and effective in the treatment of hyperprolactinemia, and better follow doctor’s orders.