| Purpose: Contrast observation of Chinese and western medicine combined with western medicine treatment, in improving the angina pectoris clinical symptoms, reduce the incidence of myocardial infarction and reascularization, MMP- 9and PAPP-a level of advantage.Methods: Choose from October 2014 to January 2015 UA patients with 60 cases, divided into two groups at random, double blind, placebo, multi-center, parallel experiments. Patients can be divided into western medicine plus placebo group and routine western medicine therapy and routine therapy and red soup of t2 dm group. Use 4 weeks to 1 week, 2 weeks after treatment for 4 weeks, 3 weeks, curative effect evaluation points, observation of angina pectoris, acute myocardial infarction(mi), the improvement of the incidence of reascularization, MMP- 9, PAPP-a indicators, such as the quality of life index.Result : Group and treatment group to improve the symptoms of angina pectoris, myocardial infarction, reduce the incidence rate of unstable angina pectoris reascularization, improve PAPP and MMP- 9- A indicators are significantly difference compared with before treatment(P < 0.05), and the treatment group was significantly better than that of control group(P < 0.05). And can significantly improve the patient’s quality of life, and the treatment group is significantly higher than control group(P < 0.05). In electrocardiogram(ecg) treatment, all have significant improved than before treatment(P < 0.05), ecg adverse situation can change, and the treatment group have a significant advantage(P < 0.05). Under the security indexes monitoring, treatment before and after two groups of patients during treatment with no exceptions, no adverse events.Conclusion: Combining traditional Chinese and western medicine treatment of UA treatment effect is significantly better than single western medicine to standardize drug treatment, the clinical treatment effect is also very clear, and safety, and can improve the symptoms of angina pectoris, reduce the incidence of myocardial infarction and revascularization, improvement of MMP- 9 and PAPP-a indicators, enhanced activity endurance and improve the quality of life has more clinical advantages. |