Variation Of Visual Acuity And Retinopathy Between Type 2 Diabetic Patients And No Diabetic Patients After Phacoemulsification Surgery And IOL Implantation

Objective:By observing the variation of best corrected visual acuity,the macular organizational structures and diabetic retinopathy between type 2 diabetic patients with nonproliferative diabetic retinopathy and no diabetic patients after phacoemulsification surgery and IOL implantation,in order to evaluate the influence of phacoemulsification surgery on macular foveal retinal thickness and diabetic retinopathy,in order to find out the risk factors of macular edema and Diabetic retinopathy(DR) progression.Method:50 eyes of cateract in type 2 diabetics with nonproliferative diabetic retinopathy were chosen randomly.The oprated eyes were assigned to the diabetic treatment group,while the other 50 no-oprated eyes as no treatment group. Both of the two groups had the same stage of DR. Optical coherence tomography (OCT)、best corrected visual acuity (BCVA) were performed at pre-operation and post-operative 1day,7days,1 month,and 3 months in two guoups. We compared FRT、BCVA with the data that obtained. DR were examined at pre-operation and post-operative 3 months in both guoups by FFA (fundus fluorescein angiography) to clear the stage of DR. Using the variance analysis of repeated measurement data, Matching t test to analysis the related factors.Using SPSS17.0 as analysis software.Results:All operated eyes have been got good visual outcome after surgery,and tended towards stabilily at 7days.Macular foveal retinal thickness (FRT):the two groups had no statistically significant difference before surgery, (P>0.05). On the first day,the treatment group 148.8±17.1 μm, no treatment group 148.2±18.4μm, ((P=0.417,>0.05)) no statistically significant difference. On the 7 days, treatment group 171.5±19.2μm, no treatment group 148.8±16.1μm, (P=0.028<0.05) the difference was statistically significant. At 1 month, treatment group224.4±33.8μm, no treatment group148.5±13.5μm, (P=0.014<0.05),the difference was statistically significant. At 3 months, treatment group164.8±18.1μm, and no treatment group149.1±15.7μm, (P=0.224>0.05), no statistically significant difference. The overall showed a trend of recovery. According to the criterion of maculer edema, the surgery group had no positive cases lday after surgery.3 positive cases came out at 7days.1 month,3 cases still progressed,2 of them came out cystoid macular edema (CME) and 1 emerging case.3months,2 cases still had CME, but edema significantly reduced.The control group had no positive cases. Observation of DR:FFA showed 14 cases aggravated in surgery group,the incidence was 28%,among these 2 eyes with serious NPDR aggravated to PDR,and 1came out Iris neovascular glaucoma.3 cases had progressd in no treatment group,the incidence was 6%,no PDR came out.Conclusion:Type 2 diabetes patients with NPDR improved vision after phacoemulsification surgery and IOL implantation; But with high incidence of macular edema. diabetic retinopathy progressed.Objective:By observing the variation of best corrected visual acuity,the macular organizational structures between type 2 diabetic patients with nonproliferative diabetic retinopathy and no diabetic patients after phacoemulsification surgery and IOL implantation,in order to evaluate the susceptibility macular edema after phacoemulsification surgery.Method:the diabetic treatment group was exactly alike abstract 1; Randomly extract 50 homochronous cases with no diabetic patients who underwent phacoemulsification and IOL implantation as normal treatment group. Optical coherence tomography (OCT)、best corrected visual acuity (BCVA) were performed at pre-operation and post-operative 1day,7days,1 month,and 3 months in all guoups. We compared FRT、 BCVA with the data that obtained.Matching t test to analysis the related factors.Using SPSS17.0 as analysis software.Results:All operated eyes have been got good visual outcome after surgery,and tended towards stabilily at 7days.Macular foveal retinal thickness (FRT):the two groups had no statistically significant difference before surgery, (P>0.05).1 day after surgery,the diabetic groupl48.8±17.1μm, normal group148.6±16.4μm, (P>0.05) no statistically significant difference.7 days, diabetic group171.5±19.2μm, normal group158.8±26.1μm, (P<0.05) the difference was statistically significant.1 month, diabetic group224.4±33.8μm, normal group164.5±23.5μm, (P<0.05),the difference was statistically significant.3 months, diabetic groupl64.8±18.1μm, and normal group150.1±16.9μm, (P>0.05), no statistically significant difference.According to the criterion of maculer edema, the two groups had no positive cases 1day after surgery.3 positive cases in diabetic group came out at 7days.1 month,3 cases of diabetic group still progressed,2 of them came out cystoid macular edema (CME) and 1 emerging case.while normal group came out 1 positive case.3months,2 cases of diabetic group still had CME, but edema significantly reduced.while 1 positive case in the normal control group. The overall of both groups showed a trend of recovery.Conclusion:type 2 diabetes patients with NPDR improved vision after phacoemulsification surgery and IOL implantation; and morbidity and its severity of macular edema increased as well.