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A Primary Experience On Evaluation Of Elast PQ Combined The Metabolic Index In Simple Non-alcoholic Fatty Liver

Posted on:2016-07-08Degree:MasterType:Thesis
Country:ChinaCandidate:Z P LvFull Text:PDF
GTID:2284330461971269Subject:Medical imaging and nuclear medicine
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Objective:To preliminary explore the application of shear wave quantitative technique evaluation organization Nonalcoholic simple fatty liver the feasibility and its correlation with metabolism related indicators, comprehensive evaluation Elast PQ technology combined metabolic index for clinicaldiagnostic value of NAFL.Method:Application of Philips IU Elite ultrasonic diagnostic instrument Elast PQ software technology for 39cases of normal physical examination and 46cases of nonalcoholic simple fatty liver patients liver elastic hardness testing, determined by the ROC curve Elast PQ technology the diagnostic boundary value in the diagnosis of NAFL. Application of automatic biochemical analyzer collecting pieces liver function and biochemical indexes of metabolism and some common baseline parameters, comprehensive analysis of the correlation between the detection index and the index and the correlation of NAFL.Rusult:Normal people and Nonalcoholic simple fatty liver is significantly difference in Elast PQ value (t=2.227,P=0.031); By statistical calculation to large area under the ROC curve for 0.88 ± 0.02, the standard error of the area for 0.02, Elast PQ for assessing nonalcoholic simple fatty liver was statistically significant,95% confidence interal (0.817, 0.936). Elast PQ value is 3.16kpa, the sensitivity of corresponding highest and specific degree,89%、69% respectively. The case group and normal group of WHR, BMI, TG, CHO, LDL-C, Elast PQ value comparison have significant differences, there are statistical significance (P< 0.050), in NAFL group and normal group of Elast PQ value respectively have correlation with AST/ALT, WHR (r1=0.564, P1=0.018; r2=0.566, P2=0.044).Conclusions:Elast PQ technology combined the metabolic index to the diagnosis of nonalcoholic simple fatty liver is feasible, and it has a broad prospect in clinical diagnosis and treatment.
Keywords/Search Tags:Elastography Point Quantification, simple non-alcoholic fatty liver, Metabolic index, Exploratory research
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