The Effects Of Liver Congestion After Hepatectomy On The Early Remnant Liver Regeneration And Liver Function Recovery

Objective: To investigate the effects of liver congestion after hepatectomy on the early remnant liver regeneration and liver function recovery.Methods : Thirty-two patients with hepatocellular carcinoma were operated by right hemihepatectomy from Jan. 2012 to oct. 2014. According to the postoperative evaluation, the patients were devided into two subgroups, twelve cases with no liver congestion were designated as experimental group, twenty patients with liver congestion were designated as control. The volume of liver before and after operation within two weeks was assessed by threedimensional reconstruction in IQQA-LIVER system and by water test method during operation, respectively. Moreover, the regeneration rate of remnant liver was calculated. Then, the expression of AST, ALT, and TBIL in plasma were detected at day one, three, five, and seven after operation by automatic biochemistry analyzer. The expression of HGF and VEGF in serum were assessed by ELISA assay. The complications after operation were observed and involved in the study.Results: There is no difference about the rate of liver regeneration, the rate of severe complication, the expression of AST, ALT, TBIL, HGF, and VEGF between the two gruops. There is difference the retention rate of Indocyanine green after 15 minutes.Conclusions: The liver congestion after hepatectomy exerts no effects on the early remnant liver regeneration and liver function recovery.