The Research About MSCT Imaging Features Of Thyroid Nodules And MSCT Diagnostic Value For The Nodules In Different Strengthened Periods

Object:To investigate MSCT imaging features of thyroid nodules and MSCT diagnostic value for benign and malignant nodules in different enhanced periods.Materials and methods:The plain and contrast enhanced CT examination data of 143 nodules from 105 patients with thyroid nodules, confirmed by pathology were collected and analized as follow ① With the pathology results as positive control, MSCT imaging features of benign and malignant nodules were compared via analyzing MSCT signsof benign and malignant nodules (including nodule’s number, size, shape, edge, density, calcification, cystic change, enhanced features, with or no orange enhancement, coated, and the adjacent structure, the relationship with adjacent structure, cervical lymph node enlargement). SPSS 21 software was used for statistical analysis, P<0.05 had significant difference. ②The nature of 143 thyroid nodules by MSCT imaging features of benign and malignant thyroid nodules was pre-judged in order to confirm the value of MSCT in diagnosis of benign and malignant thyroid nodules as compared with pathological results. ③Combined with MSCT from plain examination, MSCT imaging of thyroid nodules under enhanced scanning check including the arterialphase, venous phase and dual phase was further studied, to prejudge the nature of thyroid nodules, and then the prejudgement was validated by pathological results, to confirm the value of each enhanced periods in diagnosis of benign and malignant nodules, P<0.05 presents to have statistical significance.Results: ①Benign and malignant thyroid nodules in the number, shape, edge, density, calcifications, cysts, enhanced features, rear edge, orange enhancement, enhanced residual ring syndrome, relationship with the adjacent structure, and enlarged cervical lymph nodes have significant statistically difference (P<0.05). but there is no significant difference in the maximum diameter and nodule position, (P>0.05). ②The accuracy rate of MSCT diagnosis for 91 cases of patients with benign thyroid nodules was 100% (91/91), the accuracy rate was 90.38% (47/52). The sensitivity of MSCT diagnosis for thyroid nodules was 96.5%, the specificity was 94.8%, the positive predictive value was 97% and the negative predictive value was 15%. ③Combined with plain MSCT scan, arterial phase, venous phase and dual phase scan by enhanced MSCT to determine the nature of benign and malignant thyroid nodules, have no significant differences between the three (X2= 1.221, P=0.976). However, the positive diagnosis rate in the venous phase of enhanced MSCT and dual phase scanning 84.62%(77/91) is higher than the artery scanning 80.22%(73/91).Conclusion:①The MSCT examination has a high value in differential diagnosis of benign and malignant thyroid nodules, a comprehensive analysis ofthyroid nodules in plain and contrast enhanced MSCT features can effectively improve the accuracy of diagnosis. ②Combined with plain MSCT scan, the enhanced MSCT scan in arterial phase, venous phase and dual phase scan todetermine the nature of benign and malignant thyroid nodules, have no significant differences. ③ The MSCT imaging from vein phase scanning, which is obtained at 60 seconds after the injection of contrast agent for enhanced scan, can meet the needs of diagnosis of benign and malignant thyroid nodules basically, and thus effectively reduce the radiation dose.