| Objective:Based on post-stroke depression and nerve function, sleep quality, quality of life related studies were analyzed in-depth study the effects of post-stroke depression and recovery of neurological deficit, combined with the effect of antidepressant treatment for the development of effective interventions provided theoretical basis. By reasonable and effective intervention to reduce the degree of depression and post-stroke depression (PSD) of patients, improve sleep quality, promote the recovery of neurological deficits, thereby improving their quality of life.Methods:1, By tracking the Court observed in December 2011-320 cases of patients with acute stroke in December 2013 admitted to the Department of Neurology, according to three months after the onset of clinical manifestations-6 months, and according to ICD-10F-06.32 organic diagnostic criteria for major depressive disorder first diagnosed patient is suffering from post-stroke depression, and then the Hamilton depression scale (Hamilton Depression Scale HAMD) (<8 points None,8-20 minutes with mild, moderate 21-35 points,> 35 points severe) evaluating the extent of depressed patients, screening depression group 64 cases,36 cases of additional non-depressed patients selected as a comparison, a total of 100 patients with acute stroke were enrolled, including 69 patients with ischemic stroke, hemorrhagic stroke 31 patients, male 56, female 44, aged 40-70 years, mean age (56.03±10.59) years.2, Then the depression group was randomly divided into two groups,32 cases in each group, one group received conventional therapy of cerebrovascular disease, depression group; another group of patients in addition to conventional medical treatment given outside cerebrovascular disease, while giving the SSRI class antidepressant medications for depression treatment groups. According to NIHSS rating scale (0 no,1-4 minutes of mild, moderate 5-15,16-25 points and severe) assessed the three groups neurologic impairment, while according to the Pittsburgh Sleep Quality Index (Pittsburgh sleep quality index PSQI) scale (0-5 well,6-10 OK, generally 11-15 minutes,16-21 minutes poor) assessment of the three groups sleep quality, according to the ADL (Activities of daily living ADL) Rating scale (≧75 minutes with mild impairment,50-74 minutes of moderate disorder, severe obstacle 0-49 points) three groups of patients assessed activities of daily living. All rates are used in the form of a questionnaire by hand operation.3, Respectively, after 2 weeks of treatment, one month, three months and six months retest, continue to observe the three groups the degree of recovery of neurological deficit, sleep quality and activities of daily living, and to assess the degree of depression was observed giving depression improve the situation.4, Selection SPSS 11.0 software for statistical analysis of the data.Results:1, After treatment, the three groups had improved neurological function, non-depressed group, the degree of recovery of neurological deficit was significantly higher than depression group (P<0.05), depression treatment group neurologic impairment degree of recovery was significantly higher than the depression control group (P<0.05).2, After treatment, the three groups PSQI is gradually reduced, have improved the quality of sleep, sleep quality improved non-depressed group than depression group (P<0.05); and depression, improve sleep quality treatment group than the control group depression (P<0.05).3, After treatment, the three groups have improved life skills, better than the non-depressed group improved depression group (P<0.05), depression, depression treatment group improved better than the control group (P<0.05).4, After the comprehensive treatment given antidepressants, depression treatment group improved significantly better than the depressive symptoms of depression in the control group (P<0.05).5, Three groups of patients a month, three-month, six-month visit, non-depressed group, whether the defect restore nerve function, sleep quality and quality of life were significantly better than the depression group (P<0.05), while depression treatment group depression was significantly better than the control group (P<0.05).Conclusion:1, After the onset of acute stroke patients, sudden verbal or physical dysfunction patients find it difficult to accept, gradually produce reactive depression. The depression on recovery of neurological function, sleep quality, quality of life will have a certain impact.2, Post-stroke depression patients after antidepressant treatment, with the improvement of depressive symptoms, sleep quality significantly improved neurological function and quality of life has also been improved and enhanced accordingly. |
PDF Full Text Request