| ObjectivesThis study prospectively observe selected 79 cases about Buzhong yiqi Tang treatment in the type of spleen and stomach qi deficiency insomnia, it is concluded that the type of spleen and stomach deficiency insomnia patients’ symptoms distribution characteristics through TCM symptoms of the patients with frequency analysis. And the study population was divided into effective and ineffective group through regarding ISI as an index of curative effect. It is concluded that there are significant differences of symptoms between two groups by chi-square analysis two groups’four diagnostic information:which differences is the key syndromes of the effective treatment in type of spleen and stomach qi deficiency insomnia; And we try to analyze the similarities and differences in Minnesota MMPI between effective and ineffective group. This study is to explore the personality characteristics of constitution of Buzhong yiqi Tang treating in type of spleen and stomach qi deficiency insomnia, to enrich and develop the traditional Chinese medicine physique study.The research takes regulating physical condition as the breakthrough point, plan to select for about ten key syndromes of Buzhong yiqi Tang treatment in type of spleen and stomach qi deficiency insomnia, in order to aid in the treatment plan about in type of spleen and stomach qi deficiency insomnia to individualized optimization:On the basis of the further improvement in the clinical curative effect of to nifying spleen qi method, we may increase the curative of the Buzhongyiqi Tang treatment in type of spleen and stomach qi deficiency insomnia.MethodsThis research through clinical prospective observational 80 cases of outpatient to make up for in Buzhong yiqi Tang treatment in type of spleen and stomach qi deficiency insomnia, which were serviced in the Psychological Sleep Department of Traditional Chinese Medicine Hospital in Guangdong Province from January 2014 to January 2015. And they filled in the "The Symptom Information of Buzhong yiqi Tang Table" so we obtained the data of 79 cases in detail. It is concluded that the type of spleen and stomach deficiency insomnia patients’symptoms distribution characteristics through TCM symptoms of the patients with frequency analysis. Because ISI pays more attention to subjective sleep quality, entries leaner, stronger operability than the Pittsburgh Sleep Quality Index Scale (PSQI), so the former ISI is adopted as a curative effect to divided the group into effective and ineffective group.We plan to extract about ten syndromes elements of Buzhong yiqi Tang treatment in the type of spleen and stomach qi deficiency insomnia between two groups by chi-square analysis. This study is based on the analysis of effective and ineffective group in MMPI scores, to conclude the distribution characteristics of the significantly increased projects.Results1.The Syndrome Elements of ResearchThis study through the single factor exploratory analysis the different characteristics in clinic information of TCM’s four diagnostic information and history comparison in the first time clinic between the effective cases and ineffective cases:this study compared the distribution of the effective with ineffective group in symptoms through the Chi-square test or Fisher’s Exact Probability Method, which key syndromes conclude dreaminess, weak pulse, depression, pulse heavy, loss of appetite, lazy to speech, sleepless, less god, heating is higher than the percentage of invalid group (in descending order of TCM symptoms percentage), and the difference was statistically significant (P<0.05). Result reveals that dreaminess and weak pulse is the core of the symptoms in Buzhong yiqi Tang treatment in type of spleen and stomach qi deficiency insomnia. But this study sample size is lesser, so expanding the sample amount to analyzing relationship between therapeutic effect and other conditions variables induce filling in the core of TCM syndromes of the effective crowd about Buzhong yiqi Tang treatment in the type of spleen and stomach qi deficiency insomnia. It is concluded that the type of spleen and stomach deficiency insomnia patients’symptoms distribution characteristics through TCM symptoms of the patients with frequency analysis: difficulty in falling asleep (62.5%), dreamness (57.5%), easy to wake up (55.0%), hard to sleep after waking (55.0%), superficial sleep (52.5%).We analyzed Psychiatric, systemic symptom, spleen and stomach function three aspects as well as characteristics of tongue, pulse of statistics. Psychiatric symptoms are mainly irritability (30.0%), depression (25.0%).2.Through the Fisher’s exact probability method, we compare the differences of MMPI variables of the effective and ineffective group in the first time clinic, which includes a total of 11 variables compared with invalid group, such as Hypochondriasis, Depression, Hysteria, Psychopathic deviate, Masculinity-femininity, Paranoia, Psychasthenia, Schizophrenia, Hypomania, Social introversion. There is no statistical significance in each variable percentage between effective and ineffective group (P>0.05), and the result suggests that there were no significant differences on the MMPI variable characteristics in Buzhong yiqi Tang treatmentin type of spleen and stomach qi deficiency insomnia between the effective and the invalid group.The distribution characteristics of MMPI between the effective and ineffec-tive group:the ranked in the top four of the significantly higher score in the MMPI are Hysteria (73.8%), Depression (66.7%), Hypochondriasis (64.3%), Psychasthenia (47.6%). Analysising of the 11 project variables of MMPI by Analysis of Pearson, the coefficient r between lie points and correction, lie points and male-female, correction and social introversion’s correlation are within 0.2-0.4, which means weak correlation with statistical significance (P<0.05)3. The ISI Scores Comparison Between Pretherapy and Post-treatmentWe define the ISI points no less than 50% as effective cases with ISI to evaluate the curative effect after the insomnia patients taking Buzhong yiqi Tang in 2 weeks. Through analysising 79 enrolled patients’the score of ISI, the mean value of the total score about ISI in pre-therapy and post-treatment respectively are 16.3 and 7.95, the overall efficiency is 68.5% with statistical difference (P<0.05).Conclusion1. There are nine key syndromes which may regard as the reference to Buzhong yiqi Tang treatment in type of spleen and stomach qi deficiency insomnia when we use Buzhong yiqi Tang to treatment in type of spleen and stomach qi deficiency insomnia, such as dreaminess, weak pulse, depression, pulse heavy, loss of appetite, lazy to speech, sleepless, less god, heating is higher than the percentage of invalid group(in descending order of TCM symptoms percentage), and the difference was statistically significant (P<0.05).Among them, the dreamness and weak pulse are the effective core elements toBuzhong yiqi Tang treatment in type of spleen and stomach qi deficiency insomnia.2. The distribution characteristics of MMPI between the effective and ineffective group:theranked in the top four of the significantly higher score of the MMPI are hysteria (73.8%), depression (66.7%), hypochondrsis (64.3%), psychasthenia (47.6%).Analysising of the 11 project variables of MMPI by analysis of Pearson, the coefficient r between lie points and correction, lie points and male-female, correction and social introversion’s correlation are within 0.2-0.4,which means weak correlation, with statistical significance (P<0.05).To explore the relationship of 11 projects in MMPI, we compared the effect-tive group with invalid group in lie points, correction, hypochondriasis, depression, hysteria, male-female, schizophrenia, paranoia, psychasthenia, hypomania, social introversionby the Fisher’s Exact Probability Method. Resu-lts show that there is no statistical significance in the percentage of each variablebetween effective and ineffective group (P>0.05), which suggests there were no significant differences on the MMPI variable characteristics with treating by Buzhong yiqi Tang in the typeof spleen and stomach qi defi-ciency insomnia.3. We define the ISI points no less than 50% as effective cases with ISI to evaluate the curative effect with the insomnia patients after the outpatient taking Buzhongyiqi Tangin 2 weeks. And the overall efficiency reaches to 65.8%, with the difference statistically significant (P<0.05). |
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