Purpose:①Discuss TCM etiology and pathogenesis, dialectical origin and current s ituation of treatment of diabetes.②Objective to evaluate the clinical curative effect and mechanism of action of Jinkui Shenqi decoction combined with western medicine in tre atment of type2diabetes mellitus patients with spleen and kidney yang.The emphasis o n the improvement of the symptoms, blood glucose and glycosylatedhemoglobin, fasting, postprandial effectsMethod:Choose66cases of spleen kidney yang deficiency type2diabetes patients.33patients were divided into treatment group,33cases in the control group. The cont rol group was given western medicine treatment, treatment group to add and subtract in Jinkui Shenqi decoction on the basis of Western Medicine. In4weeks as a course of treatment, observation of2courses. The experimental design method of t test.2group s were observed before and after treatment in patients with cold limbs, fatigue, numbne ss of the limbs, waist,other clinical symptoms and preprandial and postprandial blood g lucose, glycated hemoglobin, insulin sensitive index, changes in blood lipid indexes.Results:Patients in the treatment group after treatment in the thirsty to drink more, cold limbs, upset irritability, fatigue, easy to hunger and eating a lot, palpitations short ness of breath, numbness of the limbs, backache, polyuria symptoms before and after tr eatment there were significant differences. The treatment group and the control group af ter treatment for symptoms:cold limbs, fatigue, limb numbness, soreness of waist and t here are significant differences between. The party has better effect in cold limbs, fatigu e, limb numbness, soreness of waist and other symptoms. The treatment group and the control group after treatment, fasting, postprandial blood glucose and glycosylated hemog lobin were improved. In the treatment group and the control group after treatment, there was statistical significance in p<0.05. The party has obvious curative effect in lowering blood glucose and glycosylated hemoglobin. Two groups in FINS, IAI, BMI, TC, TG, LDL, HDL no significant difference. The party has no obvious effect on improving insu lin sensitivity and blood lipid.Conclusion:Addition and subtraction Jinkui Shenqi decoction in reducing before the meal, and has obvious curative effect on postprandial blood glucose and glycosylated he moglobin。Can significantly improve patients with cold limbs, fatigue, limb numbness, s oreness of waist and other clinical symptoms. |