Heat-clearing And Blood-activating Recipe Make The Intervention Effect On Patients Who Suffer The Renal Damage From Contrast Agent After Percutaneous Coronary Intervention Operation

Object:To explorer Heat-clearing and blood-activating recipe make the intervention effect on patients who suffer the Renal damage from contrast agent after percutaneous coronary intervention operation.Methods:In60patients underwent percutaneous coronary artery intervention treatment, it can be divided into the treatment group(Heat-clearing and blood-activating recipe group) and control group(Not Heat-clearing and blood-activating recipe group), the comparison between the two groups of patients with baseline data, treatment effect, Renal function indices, Inflammatory biomarkers, the incidence of CIN and hospital clinical events.Results:of60patients in this case, it appeared contrast induced nephropathy in two patients in contrast group.which needed renal replacement therapy;While the treatment group did not happen. In addition, both two groups have4patients’serum creatinine increase more than25%, the figure of the incidence of complications increase as hs-CRP in two groups has discrepancy,but it is not statistically significant, self-control study in the interior-group manifested that, contrast medium can cause injury to a certain extent in kidney after PCI operation, Specific performance showed that, the level of serum creatinine, Urinary β2micro-globulin, and cystatin c increased,the discrepancy is statistically significant. Also the level of hs-CRP increased apparently after operation.The comparative result between two groups show that, the group which continue using the recipe of clearing heat and invigorate the circulation of blood before and after the PCI operation can decrease the level of serum creatinine, Urinary β2micro-globulin,and cystatin c.Conclusions:percutaneous coronary intervention cause injury to a certain extent in kidney, which has a certain correlation with Inflammation Marker hs-CRP, recovery of renal function and clinical effect show more obviously after use the recipe of clearing heat and invigorate the circulation of blood, which can reduce the injury caused by contrast medium in kidney to a certain extent.