| Objective:Panic Disorder is an acute and serious anxiety disorder, which has terrible effect on life quality and social function. To explore effects of NaiKan Cognitive Therapy (NCT) on clinical symptoms and improving life qualify, social function in patients with panic disorder and provide new approaches and a strong basis for the new treatment of panic disorder.Methods:70patients with panic disorder meeting the inclusion criteria were enrolled as subjects. They are in-patients in psychiatric rehabilitation hospital of North China petroleum from December in2010to December in2011. All the patients were divided into study group (n=35) an control group (n=35) at random.Three hours a day NCT were conducted to the study group additional with the original drugs. In control group, the patients only received drug therapy and routine SP. Pre-and post-treatment, CGI, HAMA-14, SAS, SF-36were administered to all subjects.Results:In the final analysis,32patients in study group and34patients in control group were included,4patients dropped off. Pre-treatment, there are no significant difference between the study group and the control group by all the assessment tools.①Post-treatment, the CGI-S scores of patients in study group were decreased than that pre-treatment, the difference was statistically significant (t=13.392, P=0.000); The CGI-S scores of patients in control group were also lower than that pre-treatment, the difference was statistically significant (t=14.670,.P=0.000); after treatment the study group and control group had significant difference(t-2.127, P=0.037).CGI-I score between Study group and control group had significant difference(t=-2.260,P=0.027).②Post-treatment, in study group the HAMA score, somatic anxiety and psychic anxiety factors score of patients were decreased than that pre-treatment, the differences were statistically significant (t=22.200, P=0.000;t=19.320, P=0.000;t=16.275, P=0.000); The HAMA score, somatic anxiety and psychic anxiety factors score of patients in control group were also lower than that pre-treatment, the difference were statistically significant (t=23.762, P=0.000;t=25.489, P=0.000; t=17.084, P=0.000); The decrease of HAMA score and two factors in study group were more predominance than in control group, the difference is significant (t=-3.285, P=0.002;t=-3.158, P=0.003; t=-2.544, P=0.013).③Post-treatment, HAMA reductive ratio in study group was higher than that in control group(t=-2.835,P=0.006).④Post-treatment, the SAS scores of patients in study group were decreased than that pre-treatment, the difference was statistically significant (t=18.698, P=0.000); The SAS scores of patients in control group were also lower than that pre-treatment, the difference was statistically significant (t=17.497, P=0.000); The decrease of SAS scores in study group is more predominance than in control group, and the difference is significant (t=-2.403, P=0.019).⑤A increase occurred in total score and every factor score of SF-36in the pre-and post-treatment of study group (t=-10.830, P=0.003;t=-5.805,P=0.000; t=-9.050,P=0.000;t=-10.835, P=0.000;t=-4.860, P=0.003; t=-13.278, P=0.000; t=-2.396, P=0.023; t=-11.349, P=0.000). In control group, Total score and factors of PF, RP, BP, GH, SF, MH had significant difference (t-6.160, P=0.000; r=-2.963, P=0.006;t=-12.505, P=0.012;t=-8.899, P=0.000;t-8.144,t=0.000; t=-9.041, P=0.000) while factor VT and RE didn’t (P>0.05). The total score and PF, RP, BP, GH, VT, SF, RE, MH of study group were significantly higher than that in control group (t=3.432,P=0.001; r=2.429, P=0.018;t=2.268, P=0.027;t=3.613, P=0.001; t=2.567, P=0.013;t=3.143, P=0.003; t=4332, P=0.000;t=3.282,P=0.002).Conclusion:With the original drug,①Anxiety level of patients with panic disorder was more significantly decreased by NCT;②Somatic anxiety and psychic anxiety of patients with panic disorder were more remarkably mproved by DNCT;③Life quality of patients with panic disorder was more significantly improved by NCT;④As a new psychotherapy with short and easy operating, NCT has good perspect for patients with panic disorder. |
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