Research On The Role Of Somatosensory Motor Cortex By Acupuncture LI4and Face-mouth Points In The Physiological Conditions

BackgroundsRelationship between ora-facial areas and Hegu acupoints, which contains the principle of selection of acupoints according the transmission route of meridian and is the spirit of meridian theory, still remain unknown and puzzle many acupuncturists. In the recent20years, a competitive activity-dependent interaction between the face and hand representations of motor cortex has been demonstrated, in which sensory afferents play an important role. In the present study, some nerve electrophysiological and imagine techniques, including transcranial magnetic stimulation, functional magnetic resonant, muti-channel recording in vivo, etc, are applied to explore the plasticity mechanism of acupoints according the transmission route of meridian.ObjectiveCross on behalf of the cerebral cortex area dependent interaction between competitive activities, resulting function of the hand area and ora-facial area restructuring, body sensory afferent may paly an important role on that. As a starting point of this research, the use of transcranial magnetic stimulation, physiological recorder and other nerve electrophysiology and the forefront of neuron imaging techniques, probing deep "Link of Hegu (LI4)with the face and mouth" function in the areas of the brain cortex cross representative plasticity mechanism.MethodsChoose healthy volunteers from various universities in Guangzhou as the research object, select10cases of the standard subjects, in order to reduce the error, healthy subjects using self-contrast method. This research content includes two parts:1.Transcranial magnetic stimulation and acupuncture effects on motor cortex in hand:using transcranial magnetic stimulation hand area on the left side of the motor cortex, physiological recorder tests MEP of the LI4on the right hand side area, then acupuncture on the left side ST6, acusector and retaining needle for20min, again using transcranial magnetic stimulation hand area on the left side of the motor cortex, observe the changes of MEP amplitude and number of effective stimulation parts which induce a MEP.2. Transcranial magnetic stimulation and acupuncture effects on motor cortex in oral-face:5days after the transcranial magnetic stimulation for the first time, using the transcranial magnetic stimulation stimulating the face area on the left side of the motor brain, physiological recorder tests MEP of the ST6on the left side of the face, and acupuncture on the right side of LI4point, acusector and retaining needle after20min, again using transcranial magnetic stimulation stimulating face area on the left side of the motor cortex, observe the changes of MEP amplitude and number of effective stimulation parts which induce a MEP.Result(1)LI4for MEP amplitude changes before and after acupuncture has significant difference (P<0.05) within the group, ST6for MEP amplitude changes before and after acupuncture has significant difference (P<0.05) within the group, suggesting that the10healthy subjects after acupuncture effect on MEP amplitude, relative to the before acupuncture, all make it smaller.(2)Compared with the LI4and ST6have no significant difference (P>0.05) between them, showing that between the two groups the influence of the MEP amplitude and effectively stimulating parts are same.Conclusi on1. Acupuncture LI4has the influence on the oral-face area of the cerebral motor cortex;2. Acupuncture ST6has the influence on the hand area of the cerebral motor cortex.3. Between the representative of the cerebral cortex area exists the interaction of competitive.which is the premise of the restructuring of hand area and oral face area, maybe the biological mechanism of "Link of He-gu(LI4)with the face and mouth"...