The Application Of Brainstem Mapping Technology In The Brainstem Lesion Resection

Object:To investigate how to use the brainstem mapping technology to determine the position of the brainstem motion nucleus and sensory nucleus and nerve fiber, and monitor its function Continuously. Apply this technology to choose the proper operation approach, adjust the operation to try to avoid the important nucleus and nerve fiber in the brainstem lesion resection. The maximum possible reduce the injury caused by brainstem lesion resection.Method:Mapping the brainstem nerve fiber by functional MRI and select proper operation approach with the result of the mapping. Mapping the brainstem motion nucleus and sensory nucleus and nerve fiber by EMG, SSEP, BAEP, MEP and brainstem EEG, and monitor its function Continuously, designing the incision of brainstem surface and adjusting the operation in the surgery according to the result of the mapping and monitoring, so as to achieve the maximum resection of the lesion, the greatest degree of protection of brain function.Result:We have done13cases of brainstem lesion resection by brainstem mapping technology,8cases of cavernous hemangioma,4cases of glioma,1case of arachnoid cyst. the therapeutic effect is good, no patient occur distinguished deficit of neuro-function.Through a comprehensive searching in database, compare the mortality and disability rate of the brainstem lesion resection which use brainstem mapping technology with the ones which did not use, mortality and disability rate of the former was lower than the latter. Application of SPSS19.0software for statistical analysis, using the chi square test. P<0.05, the difference was statistically significant.Conclusion:Brainstem mapping can effectively reduce the the injury caused by brainstem lesion operation and represent the developing direction of brainstem lesion operation in future.