Experimental Study Of Erhuang Pill On Anti-Skin Decrepitude For D-Galactose-Induced Aging Mouse Model

On the basis of the research carried out into skin aging by experts in medicalscience,traditional and modern,as well as a further discussion on the mechanism of skinaging,use experiment method to observe the function of the ErHuang Pill for skinaging.This topic research of:Objective: Pass to the D-galactose with the result that observation of the decrepitudemodel acupuncture treatment result of small rat, and with the comparison of the matchedcontrol, verify to puncture whether ErHuang Pill have the dissimilarity of the anti- skinaging function.Methods: This experiment passes to build up second impatient decrepitude model ofsmall rat for the small rat subcutaneous injection D-galactose.Give to ErHuang Pilltreatment after twenty-one, and establish to check against the VE treatment and matchedcontrol.Sentence to death the small rat the second day after curing to be over, take the backskin part to do the organization slice to carry on organizing the appearance to learn theobservation and quantitative analysises after lose hair, remaining back skin does theorganization to strach evenly to strach evenly with the measurement medium vitality ofSOD, content of MDA, vitality of CAT, content of Hyp and content of GSH- Px.Thecovariance learns to handle the data adoption all the few±Sigma mean, the a compares theadoption t examination.Results: The high ErHuang Pill set and the model set compare the SOD increases highand the differences is obvious, the MDA lower and the difference is obvious, the CATincreases the high trend but differences not obvious, the content of Hyp increase high anddifference obvious, the epidermis and the leather increase thick and difference obvious;Themiddling ErHuang Pill and the model set compare the SOD increases high and thedifferences is obvious, the MDA lower but the difference is not obvious, the CAT increasesthe high trend but differences not obvious,the content of Hyp increase the high trend but thedifference is not obvious, the epidermis and the leather increase thick and differenceobvious.Conclusion: The ErHuang Pill has the certain anti- skin decrepitude function forD-galactose-induced aging mouse model.