| Objective: to observe the remove warts syrup treatment of verruca plana (qi and blood stasis type)clinical curative effect and its influence on serum levels of IL-10, to explore the diagnosis andtreatment remove warts syrup the mechanism of action of qi and blood stasis type flat warts.Methods: will be included in the standard of60patients with verruca plana qi stagnancy and bloodstasis syndrome, were randomly divided into observation group and control group, the observationgroup of33cases, control group27cases, two groups of patients in such aspects as age, duration,sex there was no significant difference (P>0.05); Observation group quyu warts syrup,40ml(reducing children’s discretion), every time after meal half an hour in the morning and evening eachsuit once; Control group oral levamisole, every time50mg (reducing children’s discretion), threetimes a day, take11days, three days after serving three days, stop11days; Two groups at the sametime the use of vitamin A acid cream, in January, for1course of treatment, after two courses ofitchy skin changes of two groups of patients and the degree of evaluation and statistical analysis.Enzyme linked immunosorbent method to detect the two groups before and after treatment thelevels of serum IL-10, and the determination of10cases of healthy person serum IL-10as afoundation for normal value.Results:1, two groups of lesion score: the control group after treatment was detected score was9.38+/-2.815, observation group after treatment skin score was11.45+/-6.01; Compared with the controlgroup (P <0.01, with significant difference.2, Chinese medicine symptom score, the control group after treatment was detected score was14.81+/-4.37, observation group after treatment skin score was13.82+/-4.51; Compared withcontrol group, P=0.847(P st130.05), no statistical significance.3, clinical curative effect observation: group a total of33cases,7cases cured,8cases weremarkedly effective, improvement in13cases, invalid in5cases, total effective rate was84.85%;Control group a total of27patients were cured,1cases,4cases had marked effect, improvement in 10cases,12cases ineffective, the total effective rate was55.56%. Compared with the control groupcurative effect is superior to the control group.4, Dermatology Life Quality Index ((Dermatology Life Quality Index) rating: the control groupafter treatment DLQI Index was15.58+/-3.24, observation group after treatment DLQI was12.45+/-3.63, compared with the control group after treatment (P <0.05, with statisticalsignificance.5, Hamilton anxiety rating: the control group after treatment HAMA was41.63+/-3.37,observation group of HAMA after treatment was46.64+/-1.98, compared with the control groupafter treatment (P st130.05, no statistical significance.6, IL-10changes: the control group after treatment of IL-10was0.15+/-0.07, observationgroup of IL-10after treatment was0.32+/-0.22, compared with the control group after treatment(P <0.01, has obvious statistical significance.Conclusion:Remove warts syrup by promote the healing of skin lesions as soon as possible, improve patientswith symptoms of TCM, to improve the clinical cure rate, reduce the patient’s anxiety, improve thequality of life. Its mechanism may be associated with lower serum IL-10patients. |