Evaluate The Carotid Elasticity And Hemodynamic Changes In Hypertension Patients With Atrial Fibrillation

PartIUsing E-tracking technique to evaluate the carotid elasticityin patients with hypertension combined with atrial fibrillationObjective： To assess carotid elasticity in patients with essential hypertension andarterial fibrillation by E-tracking technique.Methods: Thirty-six patients with essential hypertension (EH group),37patients withhypertension and atrial fibrillation (hypertension with atrial fibrillation group) and35healthy volunteers (control group) were selected. Carotid artery stiffness parameters (β),modulus of elasticity (Eρ), compliance (AC), carotid artery intima-media thickness(IMT) and diameter (D) were measured and recorded by E-tracking technique.Results： Compared with the control group, β, Eρ, IMT and D in hypertension groupand hypertension with atrial fibrillation group increased, AC decreased; Compared withthe hypertension group, β, Eρ and IMT in atrial fibrillation with hypertension groupincreased, AC decreased (all P<0.05). When IMT≤1.0mm without vasodilation, β, Eρ、AC comparative results in three groups were the same as above. Multiple linearregression analysis showed that age, body mass index (BMI), low density lipoproteinwere the risk factors for patients with hypertension and atrial fibrillation.Conclusion：Carotid IMT of patients with hypertension and atrial fibrillation increases,elasticity decreases. Age, BMI, low density lipoprotein cholesterol are the risk factors. E-tracking technique can early detect the modification of carotid artery elasticity beforeno obvious morphological changes, response the change of vascular endothelialfunction, It is a new index for early prediction of atherosclerosis, can preventatherosclerosis development early. PartIIEvaluate hemodynamic changes in hypertension patientswith atrial fibrillationObjective: To assess the correlation between carotid atherosis and hemodynamicchanges in patients with essential hypertension and arterial fibrillation.Methods:37patients with essential hypertension (EH group),34patients withhypertension and atrial fibrillation (hypertension with atrial fibrillation group) and36healthy volunteers (control group) underwent color Doppler ultrasonography of carotidartery. Carotid artery intima-media thickness (IMT), diameter (D) and maximum shearrate (SRmax) were measured.Results:(1) Compared with the control group, IMT and diameter in hypertensiongroup and hypertension with atrial fibrillation group increased, SRmax decreased;Compared with the hypertension group, IMT and diameter in atrial fibrillation withhypertension group increased, SRmax decreased, with statistically significant difference(P<0.05). When IMT≤1.0mm without vasodilation, SRmax comparative results are thesame as above.Conclusion: Carotid SRmax of patients with hypertension and atrial fibrillationdecreases. Hemodynamic changes is valuable to early evaluate carotid arteryatherosclerosis.