Laparoscopic And Open Surgery For Colorectal Cancer Comparing The Impact Of The Body’s Stress Response

Objective Comparison of patients with colorectal cancer open, laparoscopic surgery cases their stress response.Materials and Methods Prospective patients from our department selected a total of27cases of colorectal cancer from June2013to November2013, There are14cases in which laparoscopic resection of colorectal cancer treatment (laparoscopic group),13patients with conventional open resection of colorectal cancer treatment (open group),Collected and detected one day before the two groups of patients, postoperative1hour, after one day, after two days and after5days of serum IL-6, TNF-a, CRP, HO-1and ghrelin levels. Sex ratio and compared two groups of patients, age, number of cases complications occur, detailed records of each patient’s operative time, blood loss, postoperative pathology and postoperative hospital stay.Results open surgery group13cases, six men, seven women, and their average age was60.8years old (60.8±8.03years), mean operative time was173minutes (173±18.3minutes), intraoperative The average blood loss was129ml (129±23ml), the average hospital stay was10.5days patients (10.5±1.2days), no significant postoperative complications in patients;14cases of laparoscopic surgery group, eight males, six women, their average age was64.4years (64.4±8.5), mean operative time was217.5points (217.5±17.9), mean intraoperative blood loss was82.9ml (82.9±26ml) average postoperative hospital stay7.7days (7.7±0.9days), postoperative patients with no significant complications.Two groups of patients before surgery one day of IL-6, TNF-α, CRP, HO-1and ghrelin levels were not significantly different (P>0.05); Laparoscopic surgery one hour, one day, two days, five days of IL-6, TNF-α, CRP, ghrelin were lower than the open group (P <0.05), HO-1, although lower than the laparotomy group, but not statistically significant (P>0.05).Conclusion This experiment confirmed that the smaller the impact of laparoscopic surgery for colorectal cancer in the body’s response to stress. However, due to too few experimental samples still need further clinical studies to assess potential therapeutic laparoscopic resection of colorectal cancer risk exists.