Objective To explore the clinical differentiation of syndromes character and evolvement law of the course during the thoracic radiation therapy for the study of clinical, and then to explore the classification based on syndrome differentiation, and for the establishment of TCM treatment and the prevention and treatment of side effects to provide more theoretical basis.Methods To collect the clinic TCM data of patients with thoracic radiation therapy, analyze its syndrome complex law, the prospective study method, questionnaire data collection technology are used and a database of syndromes. Summarize the syndrome complex law with clustering analysis ways. Summarize principal symptom to syndrome diagnosis of TCM with the Logistic regression analysis. To summarize the syndrome complex and evolvement law of the course during the actiontheraphy of thoracic neoplasms.Result There are90cases in the prospective study and no loss. According to variance cluster, the symptom of patients with thoracic radiation therapy could be divided into five nest of syndrome. On the basis of results of Logistic regression analysis, we gained principal symptom statistically significant to syndrome diagnosis of TCM. The phlegm-dampness syndrome:coughing up white phlegm, top-heavy, drowsiness, dry mouth and don’t want to drink, slippery pulse. The heat-toxin syndrome:coughing up yellow phlegm, dry mouth and like to drink cold water, constipation, rapid pulse. The blood stasis syndrome:hemoptysis with dark color, not to swallow to gargle, purple tongue or with ecchymosis, taut pulse. The qi deficiency syndrome:spontaneous sweating, tired weakness, enlarged tongue, weakness pulse. The yin deficiency syndrome:dysphoria in chest-palms-soles, soreness and weakness of waist and knees, night sweating, less coating, thin pulse. The dominating syndromes complex of TCM, during the early stage is phlegm-dampness syndrome (including46.67%), during the actinotheraphy is the heat-toxin syndrome (including43.33%), at the end of the actinotheraphy is the yin deficiency syndrome (including31.11%), meanwhile, qi deficiency increased significantly.Conclusion According to results of cluster analysis and Logistic regression analysis, familiar syndromes of thoracic neoplasms could be sum up to five kinds: the phlegm-dampness syndrome, the heat-toxin syndrome, the blood stasis syndrome, the qi deficiency syndrome and the yin deficiency syndrome. The key to pathology is dampness, stasis, heat and deficiency. Along with the course through of the actinotheraphy, the proportion of the heat-toxin syndromes increase and along with the process of the time, the proportion of qi and yin deficiency syndromes is increased.The defection is the number of total cases is small, which will influence the universality of the conclusion to extrapolate. If we could add the numbers of swatch, the result of our study would be more persuasion. |