The Clinical Value Of Arterial Health Assessment System

Objective: Arterial Health Package （Arterial Health Package， AHP） edgeautomated analysis software combined with high frequency colour to exceed thetraditional manual measurement method for observation of ischemic cerebrovasculardisease of carotid intima-media thickness and related parameters, clear edge of AHPautomation measurement analysis software to forecast the incidence of ischemiccerebrovascular disease clinical application value.Methods: Check Equipped with AHP edge of automated measurement analysissoftware high frequency colour to exceed in August2012and January2013in ourhospital neurology hospital treatment of ischemic cerebrovascular disease,114cases,among which62were male, female,52cases, mean age61.24±8.71years old.Includedin the request, age40to70years old, no malignant lesions, autoimmune diseases, noserious liver and kidney diseases (liver fibrosis Ⅲ below level, nephropathy Ⅲbelowlevel), statins use less than3months[9].Using Siemens ACUSON S2000color doppler ultrasonic diagnostic apparatus,9L4linear array broadband probe, the probe is4.0～9.0MHz frequency, equipped withAHP edge automation measurement evaluation software.Detailed history, in the morning on an empty stomach quiet condition, blood lipidsand blood pressure, informed patient checking purpose and the detailed inspectionprocess, and patients after cooperation, instruct patients to keep quiet state, supine, neckextension, head to one side, as far as possible exposure to the carotid artery.In two-dimensional ultrasonic mode, adjust the probe frequency to8.0MHz, fixeddetection depth is4cm, and connected to the electrocardiogram (ECG). Will probegently placed in the supraclavicular fossa carotid artery segment, a transverse begin toscan, probe from foot lateral side, until the mandibular Angle, after determine theposition of carotid artery bifurcation, will probe rotate90DHS, slitting and observation.In respectively slitting and scan clear far period of common carotid arteries, the middle section, expands and after internal carotid artery wall image, each recording a longabout5s dynamic images, for the late replay analysis.Playback image, careful observation of the extracranial carotid artery, sure-in thefilm Thickness in the carotid artery in the middle (Intima-Media Thickness, IMT), inthe case of a change in R wave starting place to get a clear common carotid artery in themiddle section of the wall images after, freeze image, select back wall IMT the thickestarea (including the patches), measure the bilateral common carotid artery lumen-liningin junction with film-the distance between the outer membrane junction, measuredthree times in a row, calculate average value.The obtained data using SPSS17.0analysis software for statistical analysis.Measurement data to mean±standard deviation, according to measurement data usingPearson correlation analysis correlation, correlation grade adopts Spearman correlationanalysis correlation data, measurement data using independent sample t test to comparethe differences of each data, level data using rank and inspection comparison betweengroups of the differences between data, with P＜0.05for the difference is statisticallysignificant.Results:1.The AHP software automatic measurement of article58of transient ischemicattack group of common carotid artery IMT after middle period of wall, the average was0.63±0.14mm.Manual measuring228carotid artery IMT after middle period of wall,one on the right side of114, the average was0.87±0.23mm, the left side of the article114, the average was0.98±0.33mm.AHP software automatic measuring228carotid artery IMT after middle period ofwall, one on the right side of114, the average was0.72±0.20mm, the left side of thearticle114, the average was0.80±0.27mm.2.AHP software automatic measuring bilateral common carotid artery IMT andmanual measuring wall after middle period of bilateral common carotid artery IMTwere positively correlated, after middle period of wall on the right side of thecorrelation coefficient was0.891(P＜0.01), the left side of the correlation coefficientwas0.890(P＜0.01).AHP software automatic measurement and manual measurement on the right sidecommon carotid artery IMT wall after middle period of no significant difference (P＞0.05), the left side of AHP software automatic measurement and manual measurementof carotid artery IMT wall after middle period of no significant difference(P＞0.05). 3.On the right side of CIMT percentile and ischemic cerebrovascular diseasewas positively associated with the degree of progress, the correlation coefficientwas0.207, P value is0.027(P＜0.05).On the left side of the CIMT percentile and ischemic cerebrovascular diseasewas positively associated with the degree of progress, correlation coefficient was0.187, P value is0.047(P＜0.05).4.Transient ischemic attack group company three highs sends with transientischemic group biological age no difference (P＞0.05), between its biological age andtransient ischemic attack group have no difference(P＞0.05) between vascular age,transient ischemic hair company three highs set their biological age and vascular agehad significant difference (P＜0.01), between transient ischemic attack group companythree highs sends with transient ischemic vascular age between has significantdifference(P＜0.01).Conclusion: The experimental ultrasonic automation measurement analysis, AHPwas applied to114patients were retrospectively analyzed.1.Automatic measuring CIMT proved AHP is credible.2.CIMT percentile method and carotid artery vascular age two new indexes, inpredicting the future risk of ischemic cerebrovascular disease have clinical applicationvalue.